1346435-32-2Relevant academic research and scientific papers
Lewis acid catalyzed protective opening of epoxides with pivaloyl halides
Vijaya Kumar, Tulam,Bharadwaj, T. Vinay,Ukkanti,Mainkar, Prathama S.
, p. 2795 - 2797 (2015/12/11)
An efficient protocol of shorter reaction times for protective opening of epoxides (POE) with pivaloyl halides under solvent-free conditions in presence of Lewis acid catalysts has been developed.
Protective opening of epoxide using pivaloyl halides under catalyst-free conditions
Rao, Chitturi Bhujanga,Rao, Dasireddi Chandra,Venkateswara, Mallem,Venkateswarlu, Yenamandra
supporting information; experimental part, p. 2704 - 2707 (2011/12/05)
An efficient and environmentally benign protocol for protective opening of epoxide (POE) with pivaloyl halides in solvent-free conditions and in aqueous media under catalyst-free conditions has been developed. The green reaction conditions, simple work-up procedures, high yields and broad scope of the reaction illustrate the good synthetic utility of this method. The key advantages of the reaction are regioselectivity and reconvertability of products into their prior epoxides in the presence of mild reaction conditions.
