2211-94-1

Usage

Uses

Used in Polymer Industry:
2,3-EPOXYPROPYL-4-METHOXYPHENYL ETHER is used as a catalyst for the radical polymerization of styrene. It plays a crucial role in the production of polystyrene and other styrene-based polymers, which are widely used in the manufacturing of plastics, rubber, and various other materials.
As a catalyst, 2,3-EPOXYPROPYL-4-METHOXYPHENYL ETHER helps to initiate the polymerization process by forming free radicals that react with styrene monomers. This reaction leads to the formation of a growing polymer chain, which eventually results in the formation of the desired polymer. The use of this catalyst allows for better control over the polymerization process, resulting in polymers with specific properties tailored to various applications.
In addition to its application in the polymer industry, 2,3-EPOXYPROPYL-4-METHOXYPHENYL ETHER may also find use in other industries where its unique chemical properties can be leveraged for specific purposes. However, based on the provided materials, the primary application of 2,3-EPOXYPROPYL-4-METHOXYPHENYL ETHER is as a catalyst in the radical polymerization of styrene.

Upstream product

• 150-76-5 4-methoxy-phenol 
• 106-89-8 epichlorohydrin 
• 13391-35-0 allyl (4-methoxyphenyl) ether 
• 3132-64-7 1,2-Epoxy-3-bromopropane 
• 142037-06-7 (R)-1-Chloro-3-(4-methoxy-phenoxy)-propan-2-ol 
• 17131-52-1 (S)-1-O-(4-methoxyphenyl)glycerol 
• 70987-78-9 (S)-Glycidyl tosylate 
• 115314-14-2 (2s)-(+)-glycidyl 3-nitrobenzenesulfonate 
• 2211-94-1 2,3-epoxypropyl p-methoxyphenyl ether 
• 51594-55-9 (R)-(-)-epichlorohydrin 
• 124-38-9 carbon dioxide 
• 130998-35-5 Toluene-4-sulfonic acid (S)-2-hydroxy-3-(4-methoxy-phenoxy)-propyl ester 
• 141987-52-2 Acetic acid (S)-1-chloromethyl-2-(4-methoxy-phenoxy)-ethyl ester 
• 60456-23-7 (S)-oxiranemethanol 

Downstream Products

• 32569-58-7 1-(4-methoxy-phenoxy)-3-piperidin-1-yl-propan-2-ol 
• 51023-59-7 M 66368 
• 32017-84-8 1-methoxy-3-phenoxy-propan-2-ol 
• 39144-44-0 1-methoxy-3-(4-methoxyphenoxy)propan-2-ol 
• 122-60-1 Phenyl glycidyl ether 
• 150-76-5 4-methoxy-phenol 
• 108-95-2 phenol 
• 82255-30-9 C₁₁H₁₆N₂O₅ 
• 82255-40-1 C₂₁H₂₈N₂O₈ 
• 17131-52-1 3-(4-methoxyphenoxy)-1,2-propanediol 
• 93624-87-4 α-p-methoxy phenoxymethyl β-N-carbomethoxy aminoxyethanol 
• 93624-91-0 1-{N-[2-Hydroxy-3-(4-methoxy-phenoxy)-propyl]aminooxy}-3-(4-methoxy-phenoxy)-propan-2-ol 
• 128263-86-5 N-[2-[[2-Hydroxy-3-(4-methoxyphenoxy)propyl]amino]ethyl]-4-(1H-imidazol-1-yl)benzamide 
• 119350-36-6 3-(4-toluenesulfonyl)-5-(4-methoxyphenoxymethylene)-2-oxazolidone 

Relevant academic research and scientific papers

Design, synthesis and biological evaluation of imidazole and triazole-based carbamates as novel aromatase inhibitors

In the search for novel aromatase inhibitors, a series of triazole and imidazole-based carbamate derivatives were designed and synthesized. Final compounds were thus evaluated against human aromatase by in vitro kinetic experiments in a fluorimetric assay in comparison with letrozole. The effect of most active derivatives 13a and 15c was then evaluated in vitro on the human breast cancer cell line MCF7 by MTT assay, cytotoxicity assay (LDH release) and cell cycle analysis, revealing a dose-dependent inhibition profile of cell viability and low micromolar IC50 values. In addition, docking simulations were also carried out to elucidate at a molecular level of detail the binding modes adopted to target human aromatase.

Substituted diaryl compound and preparation method and application thereof

The invention relates to the field of medicinal chemistry, in particular to a substituted diaryl compound (I). The preparation method comprises the following steps: medicine preparation and medical application thereof. Test results show that the substituted diaryl compound has a good inhibition effect on human lung cancer (A549), human ovarian cancer (SKOV3), human melanoma (A375) and human colon cancer (LOVO) cells. Formula (I):

DIACYLGLYCEROL LACTONE COMPOUND, PREPARATION METHOD THEREFOR, AND IMMUNOSTIMULATOR CONTAINING SAME AS ACTIVE INGREDIENT

Disclosed are a novel diacylglycerol lactone compound for improving immunity and inhibiting infection by promoting neutrophil movement, a preparation method therefor, and an immunostimulator containing same as an active ingredient. The diacyloglycerol lactone compound is represented by chemical formula 1 of the specification. In chemical formula 1, R1 and R2 are respectively N and independently a C2-30 fatty acid group.

Chemoselective Epoxidation of Allyloxybenzene by Hydrogen Peroxide Over MFI-Type Titanosilicate

The chemoselective synthesis of 2-(phenoxymethyl)oxirane from allyloxybenzene is achieved with over 90 % yield in a sustainable reaction system using titanium-substituted silicalite-1 (TS-1) as a catalyst, hydrogen peroxide (H2O2) as an oxidant, and a mixture of MeOH/MeCN as a solvent at 40 °C. No acid-catalyzed side reactions prompted by the Lewis acidity of the Ti active site in TS-1 are observed. The TS-1 catalyst can also promote the formation of oxiranes from various p-substituted allyloxybenzenes in good yields. The reaction mechanism is investigated through the reaction with other allyloxy compounds. The results, which are supported by DFT calculations, indicate that an active species of Ti peroxides formed from the reaction of TS-1 with H2O2 selectively oxidizes the allyloxybenzene to 2-(phenoxymethyl)oxirane.

Engineering a homochiral metal-organic framework based on an amino acid for enantioselective separation

A chiral metal-organic framework possessing an open amphiphilic channel is constructed from a dicarboxylate ligand derived from an amino acid and is shown to be an efficient and recyclable chiral solid adsorbent, which is capable of separating racemic secondary alcohols, epoxides, and ibuprofen with very high enantioselectivity.

Design, synthesis and biological evaluation of novel desloratadine derivatives with anti-inflammatory and H1 antagonize activities

To improve the anti-inflammatory activity of desloratadine, we designed and synthesized a series of novel desloratadine derivatives. All compounds were evaluated for their anti-inflammatory and H1 antagonistic activities. Among them, compound 2c showed the strongest H1 antagonistic and anti-inflammatory activity. It also exhibited promising pharmacokinetic profiles and low toxicity. All these results suggest that compound 2c as a novel anti-allergic agent is worthy of further investigation.

A facile and efficient method for synthesis of β-iodocarboxylates from terminal epoxides

A facile and efficient method has been developed for synthesis of β-iodocarboxylates in the presences of Ph3P/I2. Starting from epoxides, a series of β-iodocarboxylate compounds can be directly obtained in toluene media with excellent yields. Moreover, the method was successfully applied for the late-stage modification of natural products, such as isosteviol and vincamine derivatives, achieving the corresponding β-iodocarboxylates in good yields.

Chiral Bifunctional Metalloporphyrin Catalysts for Kinetic Resolution of Epoxides with Carbon Dioxide

Chiral binaphthyl-strapped Zn(II) porphyrins with triazolium halide units were synthesized as bifunctional catalysts for kinetic resolution of epoxides with CO2. Several catalysts were screened by changing the linker length and nucleophilic counteranions, and the optimized catalyst accelerated the enantioselective reaction at ambient temperature to produce optically active cyclic carbonates and epoxides.

Modulators of cell adhesion, methods and compositions therefor

Compounds with activity as modulators of cell adhesion are disclosed. The compounds are derivatives of piperidin-4-amine. In some embodiments, a compound can be linked to a targeting agent, a pharmaceutically active substance and/or a support material. Methods for enhancing or inhibiting classical cadherin-mediated functions are also disclosed. The compounds can be used for the treatment or prevention of a variety of diseases including cancer. Compositions and devices, including skin patches comprising a compound are also disclosed. In addition, methods of synthesis of the compounds are provided.

Montmorillonite K10 catalyzed highly regioselective azidolysis of epoxides: A short and efficient synthesis of phenylglycine

A series of β‐hydroxyazides were effectively synthesized from the regioselective ring opening of epoxides by sodium azide using montmorillonite K10 as a novel heterogeneous catalyst in aqueous acetonitrile in good to excellent yields. The utility of this method has been demonstrated by achieving a short synthesis of phenylglycine in 33.5% overall yield.