134651-23-3

Upstream product

• 358-23-6 trifluoromethylsulfonic anhydride 
• 134651-26-6 methyl 2,4-anhydro-5-O-tertbutyldiphenylsilyl-D-lyxonate 
• 87-72-9 D-Xylose 
• 130481-72-0 (S)-3,5-O-benzylidene-2-O-trifluoromethanesulfonyl-D-xylono-1,4-lactone 
• 131550-06-6 methyl 2,4-anhydro-(S)-3,5-benzylidene-D-lyxonate 
• 131614-83-0 (2S,4aR,7R,7aR)-7-hydroxy-2-phenyltetrahydro-6H-furo[3,2-d][1,3]dioxin-6-one 
• 134651-25-5 methyl 2,4-anhydro-D-lyxonate 
• 131139-12-3 methyl 2,4-anhydro-3,5-di-O-benzyl-D-lyxonate 
• 134651-22-2 (2R,3R,4R)-4-(tert-Butyl-diphenyl-silanyloxymethyl)-3-hydroxy-oxetane-2-carboxylic acid methyl ester 
• 134651-21-1 methyl 2,4-anhydro-D-ribonate 
• 131139-13-4 methyl 2,4-anhydro-3,5-di-O-benzyl-D-ribonate 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 15384-37-9 D-xylono-1,4-lactone 

Downstream Products

• 787572-21-8 methyl 2,4-anhydro-5-O-tertbutyldiphenylsilyl-D-arabinonate 
• 195000-99-8 (4R,5S,6S)-6-((R)-1-Hydroxy-ethyl)-3-{(2R,3S,4R)-2-hydroxymethyl-4-[(4-nitro-benzyloxycarbonylamino)-methyl]-oxetan-3-ylsulfanyl}-4-methyl-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 195001-00-4 (4R,5S,6S)-6-((R)-1-Hydroxy-ethyl)-3-{(2S,3S,4R)-2-iodomethyl-4-[(4-nitro-benzyloxycarbonylamino)-methyl]-oxetan-3-ylsulfanyl}-4-methyl-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 195000-72-7 [(2R,3S,4R)-4-(tert-Butyl-diphenyl-silanyloxymethyl)-3-(4-methoxy-benzylsulfanyl)-oxetan-2-ylmethyl]-carbamic acid 4-nitro-benzyl ester 
• 195000-95-4 (4R,5S,6S)-3-((2R,3R,4R)-2-Azidomethyl-4-methoxycarbonyl-oxetan-3-ylsulfanyl)-6-((R)-1-hydroxy-ethyl)-4-methyl-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 195000-97-6 (4R,5S,6S)-3-((2R,3R,4R)-2-Dimethylcarbamoyl-4-hydroxymethyl-oxetan-3-ylsulfanyl)-6-((R)-1-hydroxy-ethyl)-4-methyl-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 195000-93-2 (4R,5S,6S)-6-((R)-1-Hydroxy-ethyl)-3-((2R,3R,4R)-2-hydroxymethyl-4-methoxycarbonyl-oxetan-3-ylsulfanyl)-4-methyl-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 195000-70-5 [(2R,3S,4R)-4-Azidomethyl-3-(4-methoxy-benzylsulfanyl)-oxetan-2-ylmethoxy]-tert-butyl-diphenyl-silane 
• 195000-88-5 (2R,3R,4R)-4-(tert-Butyl-diphenyl-silanyloxymethyl)-3-(4-methoxy-benzylsulfanyl)-oxetane-2-carboxylic acid dimethylamide 
• 195000-65-8 (2R,3R,4R)-4-(tert-Butyl-diphenyl-silanyloxymethyl)-3-(4-methoxy-benzylsulfanyl)-oxetane-2-carbaldehyde 
• 195000-75-0 [(2R,3S,4S)-4-Iodomethyl-3-(4-methoxy-benzylsulfanyl)-oxetan-2-ylmethyl]-carbamic acid 4-nitro-benzyl ester 
• 195000-74-9 [(2R,3S,4R)-4-Hydroxymethyl-3-(4-methoxy-benzylsulfanyl)-oxetan-2-ylmethyl]-carbamic acid 4-nitro-benzyl ester 
• 195000-68-1 [(2R,3S,4R)-4-(tert-Butyl-diphenyl-silanyloxymethyl)-3-(4-methoxy-benzylsulfanyl)-oxetan-2-yl]-methanol 
• 195000-79-4 ((2R,3S,4R)-4-Hydroxymethyl-3-mercapto-oxetan-2-ylmethyl)-carbamic acid 4-nitro-benzyl ester 

Relevant academic research and scientific papers

Oxetane cis- and trans β-amino-acid scaffolds from d-xylose by efficient SN2 reactions in oxetane rings: Methyl and hydroxymethyl analogues of the antibiotic oxetin, an oxetane β-amino-acid

Highly regioselective reactions of a benzylidene-protected oxetane with (i) triethylsilane-trifluoroacetic acid and (ii) Hanessian-Hullar bromination provide efficient access to 3-hydroxyoxetane carboxylates in which only the C-3 OH is unprotected. Subseq

Synthesis and structure-activity relationships of some novel oxetane carbapenems

Six disubstituted oxetane carbapenems were synthesized and their antibacterial profile compared with the lead amino methyl THF carbapenem as well as imipenem. The oxetane carbapenems had comparable or less activity against the Gram(-) bacteria and had red