195001-00-4

Upstream product

• 195000-72-7 [(2R,3S,4R)-4-(tert-Butyl-diphenyl-silanyloxymethyl)-3-(4-methoxy-benzylsulfanyl)-oxetan-2-ylmethyl]-carbamic acid 4-nitro-benzyl ester 
• 195000-70-5 [(2R,3S,4R)-4-Azidomethyl-3-(4-methoxy-benzylsulfanyl)-oxetan-2-ylmethoxy]-tert-butyl-diphenyl-silane 
• 195000-61-4 (2R,3R,4R)-4-(tert-Butyl-diphenyl-silanyloxymethyl)-3-(4-methoxy-benzylsulfanyl)-oxetane-2-carboxylic acid methyl ester 
• 195000-65-8 (2R,3R,4R)-4-(tert-Butyl-diphenyl-silanyloxymethyl)-3-(4-methoxy-benzylsulfanyl)-oxetane-2-carbaldehyde 
• 195000-75-0 [(2R,3S,4S)-4-Iodomethyl-3-(4-methoxy-benzylsulfanyl)-oxetan-2-ylmethyl]-carbamic acid 4-nitro-benzyl ester 
• 195000-74-9 [(2R,3S,4R)-4-Hydroxymethyl-3-(4-methoxy-benzylsulfanyl)-oxetan-2-ylmethyl]-carbamic acid 4-nitro-benzyl ester 
• 195000-68-1 [(2R,3S,4R)-4-(tert-Butyl-diphenyl-silanyloxymethyl)-3-(4-methoxy-benzylsulfanyl)-oxetan-2-yl]-methanol 
• 134651-23-3 methyl 2,4-anhydro-5-O-tertbutyldiphenylsilyl-3-O-trifluoromethanesulfonyl-D-lyxonate 
• 134651-26-6 methyl 2,4-anhydro-5-O-tertbutyldiphenylsilyl-D-lyxonate 
• 134651-25-5 methyl 2,4-anhydro-D-lyxonate 
• 131139-12-3 methyl 2,4-anhydro-3,5-di-O-benzyl-D-lyxonate 
• 93711-81-0 (4-nitrophenyl)methyl (4R,5R,6S)-3-[(diphenoxyphosphinyl)oxy]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate 
• 195000-80-7 ((2R,3S,4S)-4-Iodomethyl-3-mercapto-oxetan-2-ylmethyl)-carbamic acid 4-nitro-benzyl ester 

Relevant academic research and scientific papers

Synthesis and structure-activity relationships of some novel oxetane carbapenems

Six disubstituted oxetane carbapenems were synthesized and their antibacterial profile compared with the lead amino methyl THF carbapenem as well as imipenem. The oxetane carbapenems had comparable or less activity against the Gram(-) bacteria and had red