134665-24-0

Basic information

• Product Name: 2-(2,2-diethoxyethyl)-1,3-propanediol monoacetate
• Synonyms: 1,3-Propanediol, 2-(2,2-diethoxyethyl)-, monoacetate, (S)- (9CI);(S)-4,4-diethoxy-2-(hydroxymethyl)butyl acetate;(S)- (9CI);4,4-Diethoxy-2-(hydroxyMethyl)butyl acetate;2-(2,2-diethoxyethyl)-1,3-propanediol monoacetate;1,3-Propanediol, 2-(2,2-diethoxyethyl)-,monoacetate,(S)-
• CAS NO: 134665-24-0
• Molecular Formula: C11H22O5
• Molecular Weight: 234.29
• Product Categories: API intermediates
• Mol File: 134665-24-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 314.5°Cat760mmHg
• Flash Point: 109.8°C
• Appearance: /
• Density: 1.043g/cm³
• Vapor Pressure: 3.99E-05mmHg at 25°C
• Refractive Index: 1.444
• CAS DataBase Reference: 2-(2,2-diethoxyethyl)-1,3-propanediol monoacetate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2,2-diethoxyethyl)-1,3-propanediol monoacetate(134665-24-0)
• EPA Substance Registry System: 2-(2,2-diethoxyethyl)-1,3-propanediol monoacetate(134665-24-0)

Safety Data

• Hazardous Substances Data: 134665-24-0(Hazardous Substances Data)

Usage

General Description

2-(2,2-diethoxyethyl)-1,3-propanediol monoacetate, also known as DEPM, is a chemical compound used as a solvent or as a raw material in the production of other chemicals. It is a clear, colorless liquid with a faint odor, and it is insoluble in water but soluble in many organic solvents. DEPM is often used as a solvent for cellulose esters, resins, and dyes, and it is also used as a plasticizer in vinyl resins and nitrocellulose lacquers. Additionally, DEPM is used in the production of pharmaceuticals, flavors, and fragrances. Its low volatility and high boiling point make it suitable for use in a wide range of applications.

InChI:InChI=1/C11H22O5/c1-4-14-11(15-5-2)6-10(7-12)8-16-9(3)13/h10-12H,4-8H2,1-3H3/t10-/m0/s1

Upstream product

• 108-05-4 vinyl acetate 
• 55387-85-4 3-hydroxymethyl-4-hydroxybutanal diethyl acetal 

Relevant articles and documents

Synthesis of acyclic nucleoside derivatives

Methods and novel intermediates of the formula: wherein R6 and R7 are lower alkyl or benzyl or R6 and R7 taken together are —CH2CH2—, —CH2CH2CH2— or —CH2CH2CH2CH2CH2—, R8 is C1-C21 alkyl or a C2-C21 monounsaturated alkenyl, which may optionally be substituted with substitution substituents independently selected from the group consisting of hydroxy, C1-C6 alkyl, C1-C6 alkoxy, C1-C6 alkoxy C1-C6 alkyl, C1-C6 alkanoyl, amino, halo, cyano, azido, oxo, mercapto and nitro, and R9 is an alcohol protecting group. The intermediates are useful for the preparation of acyclic nucleoside derivatives of the formula: where one of R1 and R2 is an amino acid acyl group and the other of R1 and R2 is a —C(O)C3-C21 saturated or monounsaturated, optionally substituted alkyl and R3 is OH or H; or a pharmaceutically acceptable salt thereof.

Synthesis of chiral 3-substituted γ-lactones and 9-furanosyl-adenine from (R)-2-(2,2-diethoxyethyl)-1,3-propanediol monoacetate prepared by lipase-catalyzed reaction

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