1346679-06-8

Basic information

• Product Name: methyl 4,6-dichloro-2-iodobenzoate
• CAS NO: 1346679-06-8
• Molecular Weight: 330.937
• Mol File: 1346679-06-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 4,6-dichloro-2-iodobenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4,6-dichloro-2-iodobenzoate(1346679-06-8)
• EPA Substance Registry System: methyl 4,6-dichloro-2-iodobenzoate(1346679-06-8)

Safety Data

• Hazardous Substances Data: 1346679-06-8(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 20776-63-0 2-amino-4,6-dichlorobenzoic acid 

Downstream Products

• 1346679-07-9 6,8-dichloro-1-oxo-1,2-dihydroisoquinoline-3-carboxylic acid 
• 1346679-09-1 methyl 6,8-dichloro-1-methoxyisoquinoline-3-carboxylate 
• 1346679-08-0 methyl 4,6-dichloro-2-[(Z)-2-methoxycarbonyl-2-(2,2,2-trifluoroacetylamino)vinyl]benzoate 

Relevant articles and documents

Application of the heck reaction for the synthesis of 1-alkoxyisoquinoline- 3-carboxylic acids esters

It has been shown that the cyclization of the methyl 2-(2,2,2- trifluoroacetylamino)acrylate arylation product using methyl 4,6-dichloro-2-iodobenzoate gives the corresponding 1-methoxyisoquinoline-3- carboxylic acid ester through loss of water rather than methanol. This feature of the condensation has been used for the synthesis of methyl 1-(tert-butoxycarbonylmethoxy)isoquinoline-3-carboxylate.