134677-28-4Relevant articles and documents
Asymmetric amplification in catalysis by trans-1,2-diaminocyclohexane bistriflamide
Satyanarayana, Tummanapalli,Ferber, Benoit,Kagan, Henri B.
, p. 251 - 253 (2007)
(Figure Presented) A strong asymmetric amplification is observed in the addition of diethylzinc on aromatic aldehydes in the presence of the bistriflamide of trans-1,2-diaminocyclohexane 3a. The asymmetric amplification originates from the insolubility of
Solvent-free direct aza-Friedel-Crafts reactions between 3,4-dihydroisoquinoline and 1- or 2-naphthols
MacLeod, Patricia D.,Li, Zhiping,Feng, Jianqing,Li, Chao-Jun
, p. 6791 - 6794 (2006)
A self-catalytic aza-Friedel-Crafts method was employed to generate 1-naphtholyl tetrahydroisoquinoline products under neat conditions. In addition, a derivative was prepared in its enantiomerically pure form and has shown moderate activity for asymmetric catalysis in the asymmetric diethylzinc addition to aldehydes.
Deciphering the mechanism behind efficient enantioselective ethylation with thiazolidine-based amino alcohols
Cacho, Vanessa R. G.,Costa, Dora C. S.,Murtinho, Dina,Nunes, Sandra C. C.,Pais, Alberto A. C. C.,Silva Serra, M. Elisa,Tavares, Nélia C. T.
, (2022/01/08)
Taking advantage of the opposite chirality of two privileged starting materials, l-cysteine and d-penicillamine, a wide range of thiazolidine-based amino alcohols was synthesized. l-Cysteine derivatives were more efficient chiral inductors than the d-peni
Linear β-amino alcohol catalyst anchored on functionalized magnetite nanoparticles for enantioselective addition of dialkylzinc to aromatic aldehydes
Ciprioti, Stefano Vecchio,De Angelis, Martina,Di Pietro, Federica,Iannoni, Marika,Pilloni, Luciano,Primitivo, Ludovica,Ricelli, Alessandra,Righi, Francesco,Righi, Giuliana,Sappino, Carla,Suber, Lorenza
, p. 29688 - 29695 (2020/10/26)
A linear β-amino alcohol ligand, previously found to be a very efficient catalyst for enantioselective addition of dialkylzinc to aromatic aldehydes, has been anchored on differently functionalized superparamagnetic core-shell magnetite-silica nanoparticles (1a and 1b). Its catalytic activity in the addition of dialkylzinc to aldehydes has been evaluated, leading to promising results, especially in the case of 1b for which the recovery by simple magnetic decantation and reuse was successfully verified. This journal is
Enantioselective Addition of Diethylzinc to Aromatic Aldehydes Using Chiral Oxazoline-Based Ligands
Aydin, A. E.
, p. 1304 - 1312 (2020/10/02)
Abstract: Chiral oxazoline ligands containing an aromatic ring were prepared fromnorephedrine and pyrrole-2-carbonitrile or 2-hydroxybenzoyl chloride. Thesynthesized ligands were used in the copper-catalyzed asymmetric addition ofdiethylzinc to aromatic aldehydes to provide optically active 1-arylpropan-1-olswith high conversion (92%) and enantioselectivity (up to 99% ee).