1346851-40-8

Basic information

• Product Name: 2-((2R,6R)-6-ethyltetrahydro-2H-pyran-2-yl)ethyl 4-nitrobenzoate
• Synonyms: 2-((2R,6R)-6-ethyltetrahydro-2H-pyran-2-yl)ethyl 4-nitrobenzoate
• CAS NO: 1346851-40-8
• Molecular Weight: 307.346
• Mol File: 1346851-40-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-((2R,6R)-6-ethyltetrahydro-2H-pyran-2-yl)ethyl 4-nitrobenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-((2R,6R)-6-ethyltetrahydro-2H-pyran-2-yl)ethyl 4-nitrobenzoate(1346851-40-8)
• EPA Substance Registry System: 2-((2R,6R)-6-ethyltetrahydro-2H-pyran-2-yl)ethyl 4-nitrobenzoate(1346851-40-8)

Safety Data

• Hazardous Substances Data: 1346851-40-8(Hazardous Substances Data)

Upstream product

• 88071-66-3 (+/-)-Oct-7-en-3-ol 
• 1346850-89-2 2-((2R,6R)-6-ethyltetrahydro-2H-pyran-2-yl)ethanol 
• 122-04-3 4-nitro-benzoyl chloride 
• 1346850-50-7 (E)-7-hydroxynon-2-enal 

Relevant articles and documents

An organocascade kinetic resolution

Products of a novel iminium-catalyzed oxa-Michael addition undergo a kinetic resolution by a subsequent enamine-catalyzed intermolecular reaction. This is a rare example of kinetic resolution by enamine catalysis and the first organocascade kinetic resolution. This resolution produces enantioenriched 2,6-cis-tetrahydropyrans and, notably, cascade products with absolute and relative configurations normally not observed using this diphenyl prolinol silyl ether. This resolution thus provides new insight into asymmetric induction in reactions employing this catalyst.