1346899-08-8Relevant articles and documents
Enantioselective bromocyclization of olefins catalyzed by chiral phosphoric acid
Huang, Deshun,Wang, Haining,Xue, Fazhen,Guan, Huan,Li, Lijun,Peng, Xianyou,Shi, Yian
, p. 6350 - 6353 (2012/02/03)
A chiral phosphoric acid catalyzed enantioselective bromocyclization of olefins is described. Various cis-, trans-, or trisubstituted ?-hydroxyalkenes and γ-amino-alkenes can cyclize under the reaction conditions to give optically active 2-substituted tetrahydrofurans and tetrahydropyrroles in up to 91% ee.