1346921-53-6

Basic information

• Product Name: L-menthyl 5-cytosin-1-yl-1,3-oxathiolane-2-carboxylate
• Synonyms: L-menthyl 5-cytosin-1-yl-1,3-oxathiolane-2-carboxylate
• CAS NO: 1346921-53-6
• Molecular Weight: 381.496
• Mol File: 1346921-53-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: L-menthyl 5-cytosin-1-yl-1,3-oxathiolane-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: L-menthyl 5-cytosin-1-yl-1,3-oxathiolane-2-carboxylate(1346921-53-6)
• EPA Substance Registry System: L-menthyl 5-cytosin-1-yl-1,3-oxathiolane-2-carboxylate(1346921-53-6)

Safety Data

• Hazardous Substances Data: 1346921-53-6(Hazardous Substances Data)

Upstream product

• 200396-19-6 (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl 5-hydroxy-1,3-oxathiolane-2-carboxylate 
• 111969-64-3 L-menthyl glyoxylate monohydrate 
• 1346921-70-7 C₁₄H₂₃ClO₃S 
• 71-30-7 Cytosine 

Downstream Products

• 173602-25-0 5-(4-amino-2-oxopyrimidine-1(2H)-yl)-1,3-oxathiolane-2-carboxylic acid 
• 134678-17-4 lamivudine 
• 131086-21-0 (+/-)-cis-N-<2-(hydroxymethyl)-1,3-oxathiolan-5-yl>cytosine 

Relevant articles and documents

AN IMPROVED PROCESS FOR THE MANUFACTURE OF LAMIVUDINE

The present invention relates to an improved process for the Manufacture of Lamivudine. A process for the preparation of essentially enantiomerically pure (-)-[2R, 5S]-4-amino-1-[2- (hydroxymethyl)-1,3-oxathiolan-5-y1]-2(1H)-pyrimidin-2-one of formula (I), from L-menthyl glyoxylate is described. Also provided is a process for preparation of (+)-1- (2R/S-Cis)-4-amino-1-[(2-hydroxymethyl)-1,3-oxathiolan-5-y1]-2(1H)-pyrimidin-2-one of formula (XII), from L-menthyl glyoxylate.