1346945-65-0

Upstream product

• 1252644-42-0 N-((1R,2R)-2-amino-1,2-bis(3-nitrophenyl)ethyl)-4-methylbenzenesulfonamide 
• 1235572-14-1 tert-butyl (1R,2R)-1,2-bis(3-aminophenyl)-2-(4-methylphenylsulfonamido)ethylcarbamate 
• 145013-05-4 tert-butyl N-({[(tert-butoxy)carbonyl]amino}methanethioyl)carbamate 
• 1252644-48-6 (1R,2R)-1,2-bis(3-nitrophenyl)ethane-1,2-diamine 
• 1346945-64-9 tert-butyl (1R,2R)-2-(4-methylphenylsulfonamido)-1,2-bis(3-nitrophenyl)ethylcarbamate 
• 35132-20-8 (R,R)-1,2-diphenylethylenediamine 

Relevant academic research and scientific papers

Synthesis of a water-soluble cationic chiral diamine ligand bearing a diguanidinium and application in asymmetric transfer hydrogenation

A novel water-soluble cationic N-monosulfonated chiral diamine ligand diguanidinium 1c was easily prepared from (R,R)-DPEN and its rhodium complex and was successfully applied in the asymmetric transfer hydrogenation of prochiral ketones and imines in water by using sodium formate and formic acid as co-hydrogen donors. Various substrates were reduced with high yields and good to excellent enantioselectivities (up to >99% ee).