134699-58-4

Upstream product

• 134715-28-9 methyl 7α,12α-diacetoxy-3-dicyanomethylenecholan-24-oate 
• 589-15-1 1-bromomethyl-4-bromobenzene 
• 6818-44-6 methyl 3,7,12-triacetoxycholan-24-oate 
• 4947-65-3 methyl 3-keto-7,12-diacetylcholate 
• 69889-89-0 methyl 7,12-diacetoxycholate 
• 22807-80-3 1-bromo-4-(tert-butoxymethyl)benzene 
• 134699-57-3 (R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-7,12-Diacetoxy-3-(4-tert-butoxymethyl-phenyl)-3-dicyanomethyl-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl]-pentanoic acid methyl ester 

Downstream Products

• 1062103-70-1 (R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-7,12-Diacetoxy-3-(4-aminomethyl-phenyl)-3-dicyanomethyl-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl]-pentanoic acid 
• 134699-59-5 methyl 7α,12α-diacetoxy-3α-(p-azidomethylphenyl)-3β-dicyanomethylcholan-24-oate 
• 149947-64-8 (R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-7,12-Diacetoxy-3-(4-aminomethyl-phenyl)-3-dicyanomethyl-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl]-pentanoic acid methyl ester 
• 149947-63-7 (R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-7,12-Diacetoxy-3-dicyanomethyl-3-(4-methanesulfonyloxymethyl-phenyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl]-pentanoic acid methyl ester 

Relevant academic research and scientific papers

Synthesis of Cyclo-bis; A Cholaphane with Reduced Flexibility and Externally-directed Functionality

A second 'cholaphane' framework is manifested in the title compound 8, which has been prepared from methyl 3α,7α,12α-triacetoxycholanoate 9 in 23percent overall yield.The synthesis involves the Knoevenagel condensation of ketone 11 with malononitrile to g

Synthesis and X-Ray Crystal Structure of a New 'Cholaphane' with Externally Directed Functionality

The 'cholaphane' 1 was synthesized in 26percent overall yield from cholic acid and its structure determined by X-ray crystallography; the molecule adopts an open conformation and is able to surround two molecules of tetrahydrofurane.