22807-80-3

Usage

Uses

Used in Pharmaceutical Industry:
1-Bromo-4-(tert-butoxymethyl)benzene is used as a key intermediate for the synthesis of various pharmaceuticals and agrochemicals, contributing to the development of new drugs and agricultural products.
Used in Polymer Production:
1-Bromo-4-(tert-butoxymethyl)benzene is utilized as a building block in the production of polymers, playing a crucial role in the creation of materials with specific properties for various applications.
Used in Dye Manufacturing:
1-Bromo-4-(tert-butoxymethyl)benzene is used in the manufacturing of dyes, where its chemical structure contributes to the color and stability of the final product.
Used in Materials Science:
1-Bromo-4-(tert-butoxymethyl)benzene has potential applications in materials science, where it may be employed to develop new materials with unique properties.
Used as a Building Block for Complex Organic Compounds:
1-Bromo-4-(tert-butoxymethyl)benzene serves as a fundamental component in the synthesis of more complex organic compounds, expanding the scope of organic chemistry.
It is important to handle 1-Bromo-4-(tert-butoxymethyl)benzene with care due to its toxic nature and potential to cause irritation to the skin, eyes, and respiratory system.

Upstream product

• 589-15-1 1-bromomethyl-4-bromobenzene 
• 75-65-0 tert-butyl alcohol 
• 873-75-6 4-bromobenzenemethanol 
• 115-11-7 isobutene 

Downstream Products

• 87736-76-3 1-<(4-tert-butoxymethyl)phenyl>-2,2,2-trifluoro-1-ethanone 
• 134699-57-3 (R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-7,12-Diacetoxy-3-(4-tert-butoxymethyl-phenyl)-3-dicyanomethyl-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl]-pentanoic acid methyl ester 
• 198016-16-9 methyl 3β-[bis(butoxycarbonyl)methyl]-3α-[(p-tert-butoxymethyl)phenyl]-7α,12α-bis(formyloxy)-24-nor-5β-cholan-23-oate 
• 198016-07-8 3β-[bis(butoxycarbonyl)methyl]-3α-[(p-tert-butoxymethyl)phenyl]-7α,12α-bis(formyloxy)-24-nor-5β-cholan-22(23)-ene 
• 198016-02-3 methyl 3β-[bis(butoxycarbonyl)methyl]-3α-[(p-tert-butoxymethyl)phenyl]-7α,12α-bis(formyloxy)-5β-cholan-24-oate 
• 87736-87-6 3-<(4-tert-butoxymethyl)phenyl>-3-trifluoromethyl-3H-diazirine 
• 87736-84-3 3-<(4-tert-butoxymethyl)phenyl>-3-trifluoromethyldiaziridine 
• 87736-89-8 1-<<4-<3-(trifluoromethyl)-3H-diazirin-3-yl>benzoyl>oxy>-2,5-pyrrolidinedione 
• 87736-88-7 3-[4-(hydroxymethyl)phenyl]-3-trifluoromethyl-3H-diazirine 
• 85559-46-2 4-[3-(trifluoromethyl)-3H-diazirin-3-yl]benzoic acid 
• 87736-78-5 1-<(4-tert-butoxymethyl)phenyl>-2,2,2-trifluoro-1-ethanone oxime 
• 87736-81-0 1-<(4-tert-butoxymethyl)phenyl>-2,2,2-trifluoro-1-ethanone O-(p-tolylsulfonyl)oxime 
• 87736-81-0 C₂₀H₂₂F₃NO₄S 
• 149947-63-7 (R)-4-[(3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-7,12-Diacetoxy-3-dicyanomethyl-3-(4-methanesulfonyloxymethyl-phenyl)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl]-pentanoic acid methyl ester 

Relevant academic research and scientific papers

Acid- and isobutylene-free synthesis of t-butyl ethers by in situ formation of 2-t-butoxy-1-methylpyridinium triflate

The title reagent is formed in situ by alkylation of 2-t-butoxypyrine. The subsequent addition of an alcohol substrate leads to the formation of t-butyl ethers without the need for isobutylene gas or acid activators.

Metallocene supported catalyst and method for preparing polypropylene using the same

The present invention relates to a supported metallocene catalyst including a novel single metallocene compound having excellent polymerization activity, and a process for producing a polypropylene having excellent processability and broad molecular weigh

Propylene Random Copolymer

Provided is a propylene random copolymer having excellent processability. The propylene random copolymer according to the present invention may exhibit high stiffness and flexural modulus together with a low shrinkage ratio, thereby being usefully applied

Cosolvent-Promoted O-Benzylation with Silver(I) Oxide: Synthesis of 1′-Benzylated Sucrose Derivatives, Mechanistic Studies, and Scope Investigation

A cosolvent-promoted O-benzylation strategy with Ag2O was developed. The cosolvent consisting of CH2Cl2 and n-hexane can not only improve the reaction solubility for carbohydrates but also increase the benzylation efficiency. The formation of byproducts is greatly inhibited in the developed method. This method is simple, mild, and highly effective, and numerous 1′-benzylated sucrose derivatives were prepared including a photoreactive (trifluoromethyl)phenyldiazirine-based sucrose. The mechanisms of benzylation with primary and secondary benzyl bromides were also elaborated. Furthermore, the application scope with alcohols, glucose, and ribose derivatives was investigated.

Synthesis of Cyclo-bis; A Cholaphane with Reduced Flexibility and Externally-directed Functionality

A second 'cholaphane' framework is manifested in the title compound 8, which has been prepared from methyl 3α,7α,12α-triacetoxycholanoate 9 in 23percent overall yield.The synthesis involves the Knoevenagel condensation of ketone 11 with malononitrile to g

4-(1-Azi-2,2,2-trifluoroethyl)benzoic Acid, a Highly Photolabile Carbene Generating Label Readily Fixable to Biochemical Agents

The title compound is synthesized starting from either 4-bromobenzyl tert butyldimethylsilyl ether (5b) or 4-bromobenzyl tert-butyl ether (5c) or - most simply - from 4-bromotoluene (5a).In the first step Br was replaced by Li using n-butyllithium, then the organometallic compounds were converted into the respective trifluoroacetophenones 6a - c with N-trifluoroacetylpiperidine.The azi moiety (diazirine) was prepared from the oximes 7a - c via O-tosyloximes 8a - c plus ammonia yielding the diaziridines 9a - c and oxidation of the latter with Ag2O.Oxidation by permanganate - of the ethers after acidic cleavage - yields the title compound 12.On irradation (λ > 300 nm) 12 by elimination of N2 with a half-life period of 22 s generates the corresponding carbene.At the same time from 12 with ca. 20percent the yellow isomeric 4-(1-diazo-2,2,2-trifluoroethyl)benzoic acid (20) is formed which is photolyzed generating the same carbene as 12.The synthesis of 20 is described starting from 4-bromobenzaldehyde. - The diazirine 12 as its N-hydroxysuccinimide ester 13, or using other methods of amide synthesis, can readily be coupled to amino functions of biochemically interesting agents thus forming photoaffinity labels.