134721-51-0

Basic information

• Product Name: C₈H₆BrNO₃
• Synonyms: C₈H₆BrNO₃
• CAS NO: 134721-51-0
• Molecular Weight: 244.045
• Mol File: 134721-51-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: C₈H₆BrNO₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₈H₆BrNO₃(134721-51-0)
• EPA Substance Registry System: C₈H₆BrNO₃(134721-51-0)

Safety Data

• Hazardous Substances Data: 134721-51-0(Hazardous Substances Data)

Upstream product

• 75-52-5 nitromethane 
• 90766-96-4 N-(2-bromobenzoyl)imidazole 
• 6630-33-7 ortho-bromobenzaldehyde 

Downstream Products

• 1377577-62-2 2-bromo-N-tosylbenzamide 

Relevant articles and documents

Facile synthesis of 2-nitromethyl aromatic ketones by insertion of benzynes into the C-C bond of α-nitroketones

A facile method to synthesize 2-nitromethyl aromatic ketones was developed. In the method, benzyne was generated in situ for the insertion to α-Nitroketones in one pot to achieve 2-nitromethyl aromatic ketones under mild conditions. Aromatic and aliphatic α-nitroketones were applied in the reaction, and the results show that aliphatic α-nitroketones gave excellent yields (up to 96%), while aromatic α-nitroketones gave moderate yields. The synthesized 2-nitromethyl aromatic ketones could be potential substrates to synthesize isoindoles.

Formation of new C-O and C-N bonds via base promoted Csp2-Csp3 bond cleavage of α-nitro ketone

A catalyst free protocol has been developed for nucleophilic Csp2-Csp3 bond cleavage of α-nitroketone in the presence of potassium carbonate to create new C-O and C-N bonds. A series of different substituted α-nitroketones could be selectively cleaved and converted into corresponding esters and tosylamides in the presence of alcohols and bromamine-T, respectively.