1377577-62-2

Basic information

• Product Name: 2-bromo-N-tosylbenzamide
• Synonyms: 2-bromo-N-tosylbenzamide
• CAS NO: 1377577-62-2
• Molecular Weight: 354.224
• Mol File: 1377577-62-2.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2-bromo-N-tosylbenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromo-N-tosylbenzamide(1377577-62-2)
• EPA Substance Registry System: 2-bromo-N-tosylbenzamide(1377577-62-2)

Safety Data

• Hazardous Substances Data: 1377577-62-2(Hazardous Substances Data)

Upstream product

• 134721-51-0 C₈H₆BrNO₃ 
• 41085-71-6 bromamine T 
• 21849-40-1 dibromamine-T 
• 6630-33-7 ortho-bromobenzaldehyde 
• 70-55-3 toluene-4-sulfonamide 
• 7154-66-7 2-bromobenzoic acid chloride 
• 88-65-3 2-bromobenzoic-acid 
• 92755-81-2 N-bromo-p-toluenesulfonamide 
• 941-55-9 4-toluenesulfonyl azide 
• 127-65-1 chloroamine-T 

Downstream Products

• 1918125-85-5 (4R,5R)-2-(2-(diphenylphosphaneyl)phenyl)-4,5-diphenyl-4,5-dihydrooxazole 

Relevant articles and documents

Controllable construction of isoquinolinedione and isocoumarin scaffolds: Via RhIII-catalyzed C-H annulation of N -tosylbenzamides with diazo compounds

A highly efficient protocol for the synthesis of isoquinolinediones by RhIII-catalyzed C-H activation/annulation/decarboxylation of N-tosylbenzamides with diazo compounds is reported. The switchable synthesis of isocoumarins was also achieved successfully via C-H activation/annulation with slight modification of the reaction conditions. Importantly, the synthetic utility of this new reaction was further demonstrated in an atom-economical and operationally convenient total synthesis of a TDP2 inhibitor derivative from commercially available starting materials.

Co-Catalyzed Synthesis of N-Sulfonylcarboxamides from Carboxylic Acids and Sulfonyl Azides

A Co-catalyzed effective synthesis of N-sulfonylcarboxamides from the reaction of carboxylic acids and organic azides in the presence of isocyanide has been developed. The protocol has the advantages of short time, low temperature, and being oxidant-free, which provides a new and simple approach for the synthesis of N-sulfonylcarboxamides in good to excellent yields with a broad substrate scope.

Formation of new C-O and C-N bonds via base promoted Csp2-Csp3 bond cleavage of α-nitro ketone

A catalyst free protocol has been developed for nucleophilic Csp2-Csp3 bond cleavage of α-nitroketone in the presence of potassium carbonate to create new C-O and C-N bonds. A series of different substituted α-nitroketones could be selectively cleaved and converted into corresponding esters and tosylamides in the presence of alcohols and bromamine-T, respectively.