134747-96-9

Upstream product

• 103588-79-0 (1,1,2,2-tetramethyleth-1-yl)-dimethylsilyl trifluoromethanesulfonate 
• 131694-73-0 (3R,3aS)-3-Hydroxy-2,2-dimethyl-2,3,3a,4,5,6-hexahydro-pentalene-1-carboxylic acid ethyl ester 
• 81927-55-1 O-benzyl 2,2,2-trichloroacetimidate 
• 134747-95-8 (3R,3aS,6R)-3-[Dimethyl-(1,1,2-trimethyl-propyl)-silanyloxy]-6-hydroxy-2,2-dimethyl-2,3,3a,4,5,6-hexahydro-pentalene-1-carboxylic acid ethyl ester 

Downstream Products

• 125184-70-5 (E)-1-{(3R,3aS,6R)-6-Benzyloxy-3-[dimethyl-(1,1,2-trimethyl-propyl)-silanyloxy]-2,2-dimethyl-2,3,3a,4,5,6-hexahydro-pentalen-1-yl}-3-trimethylsilanyl-propenone 
• 125184-69-2 (E)-1-{(3R,3aS,6R)-6-Benzyloxy-3-[dimethyl-(1,1,2-trimethyl-propyl)-silanyloxy]-2,2-dimethyl-2,3,3a,4,5,6-hexahydro-pentalen-1-yl}-3-trimethylsilanyl-prop-2-en-1-ol 
• 125184-78-3 {(3R,3aS,6R)-6-Benzyloxy-3-[dimethyl-(1,1,2-trimethyl-propyl)-silanyloxy]-2,2-dimethyl-2,3,3a,4,5,6-hexahydro-pentalen-1-yl}-methanol 
• 125184-68-1 (3R,3aS,6R)-6-Benzyloxy-3-[dimethyl-(1,1,2-trimethyl-propyl)-silanyloxy]-2,2-dimethyl-2,3,3a,4,5,6-hexahydro-pentalene-1-carbaldehyde 

Relevant academic research and scientific papers

Total synthesis of (±)-silphinene: Non photochemical cyclobutenic route to a crucial intermediate

The cyclobutenic ester 1, readily available by thermal [2+2] cycloaddition of the silyl enol ether derived from cyclopentanone with ethyl propynoate, is easily transformed into the diquinanic alcohol 3 via the bicycle [2.1.0] pentane intermediate 2. After

The cyclobutenic way to triquinanes. Synthesis of (±) silphinene

The easily accessible alcohol 2 is oxidized, after protection, to the allylic alcohol 3. The benzyl ether of this diquinanic alcohol is transformed into the triquinanic precursor 9 of (±) Silphinene, using a similar reaction sequence as described previous