13475-43-9

Upstream product

• 85-44-9 phthalic anhydride 
• 2835-06-5 phenylglycin 
• 1197-55-3 4-aminophenylacetic acid 

Downstream Products

• 40101-61-9 nitrile of N-phthaloyl-4-aminobenzoic acid 
• 162742-39-4 C₁₆H₁₀ClNO₃ 
• 2142-03-2 2-p-tolylisoindoline-1,3-dione 
• 1333108-09-0 N-[4-(3-cyanopropyl)phenyl]phthalimide 

Relevant academic research and scientific papers

Hydrogen bonding chains and rings structural motifs in new series of N-phthaloyl aminocarboxylic acid derivatives. Solid state microwave synthesis, structural chemistry, computational calculations and antimicrobial activity

A series of six N-phthaloyl aminocarboxylic acids were synthesized by using improved microwave irradiation with a multimode reactor. X-ray single crystal diffraction established the molecular structure of three N-protected aminocarboxylic acids derivatives, and spectral data agree with these in solution. The hydrogen bonding characteristics of this class of molecules are discussed on the basis of crystal structural analyses, MP2/DFT quantum calculations and Hirshfeld surfaces analyses. The relative strengths of the structural O-H?O and C-H?O hydrogen bonding chain and ring motifs are compared. Antimicrobial activities of 2-(1,3-dioxoisoindolin-2-yl)propanoic acid, 2-(1,3-dioxoisoindolin-2-yl)-3-phenylpropanoic acid and 2-(4-(1,3-dioxoisoindolin-2-yl)phenyl)acetic acid, were screened against three pathogenic strains; only the first two compounds were found to be quite sensitive against Gram +ve and Gram -ve bacterial strains, respectively. A relative structure-function relationship is observed.

Amide compounds for regulating WNT signal channel and application of compounds

The invention belongs to the technical field of medicine, and particularly relates to amide compounds for regulating a WNT signal channel and an application of the compounds. The compounds have a structure represented by a general formula I shown in the description.

2-aminothiazol-fused 2-aminoindans and 2-aminotetralins and their use

The invention relates to 2-aminothiazol-fused 2-aminoindans and 2-aminotetralins having general formula (1): wherein R1and R2, which may be identical or different, are selected from the group consisting of a hydrogen atom, alkyl or haloalkyl groups of 1 to 7 carbon atoms, (alkyl)cycloalkyl groups of 3 to 7 carbon atoms, alkenyl or alkynyl groups of 3 to 6 carbon atoms, arylalkyl having 1 to 3 carbon atoms in the alkyl moiety, while the aryl nucleus may be substituted; and n and m are 1 or 2; and the enantiomers and the acid addition salts thereof, pharmaceutical compositions containing them and their use in the preparation of medicaments having an effect on the dopaminergic system of the central nervous system and/or the circulation.