134772-92-2

Upstream product

• 138723-66-7 (2R)-2-tert-butyl-3-<(S)-2-methyl-3-phenylpropionyl>-2,3-dihydro-4(1H)-pyrimidinone 
• 134773-09-4 (R)-2-tert-Butyl-3-((S)-2-methyl-butyryl)-2,3-dihydro-1H-pyrimidin-4-one 
• 134773-12-9 (R)-3-((S)-2-Benzyl-butyryl)-2-tert-butyl-2,3-dihydro-1H-pyrimidin-4-one 
• 134773-11-8 (R)-2-tert-Butyl-3-((S)-2-ethyl-pent-4-ynoyl)-2,3-dihydro-1H-pyrimidin-4-one 

Downstream Products

• 138723-65-6 (2S)-3-<(S)-2-benzylbutyryl>-2-tert-butyl-1-carbomethoxy-2,3-dihydro-4(1H)-pyrimidinone 
• 138723-62-3 (2S)-2-tert-butyl-1-carbomethoxy-3-<(S)-2-methyl-3-phenylpropionyl>-2,3-dihydro-4(1H)-pyrimidinone 
• 134773-12-9 (R)-3-((S)-2-Benzyl-butyryl)-2-tert-butyl-2,3-dihydro-1H-pyrimidin-4-one 
• 138723-66-7 (2R)-2-tert-butyl-3-<(S)-2-methyl-3-phenylpropionyl>-2,3-dihydro-4(1H)-pyrimidinone 

Relevant academic research and scientific papers

ASYMMETRIC ALKYLATIONS OF N-ACYL DIHYDROPYRIMIDINONES

Enantiomerically pure dihydropyrimidin-4-one 1 has been employed as a chiral auxiliary for enantioselective alkylation reactions.Acylation of 1, followed by enolate formation, alkylation and acyl cleavage, affords α-alkylated carboxylic acids in high chemical yield and enantiomeric purity.