1347736-52-0Relevant academic research and scientific papers
Microwave induced three-component synthesis and antimycobacterial activity of benzopyrazolo[3,4-b]quinolindiones
Quiroga, Jairo,Diaz, Yurina,Bueno, Juan,Insuasty, Braulio,Abonia, Rodrigo,Ortiz, Alejandro,Nogueras, Manuel,Cobo, Justo
, p. 216 - 224 (2014/02/14)
Three series of novel 4-arylbenzo[h]pyrazolo[3,4-b]quinolin-5,6-diones 4, 7 and 9 have been efficiently obtained in good yields by three-component microwave assisted reaction between aminopyrazoles 1 or 6 (both 1-phenyl and 1-H substituted), 2-hydroxynaph
L-Proline-catalysed sequential four-component "on water" protocol for the synthesis of structurally complex heterocyclic ortho-quinones
Michael Rajesh, Stephen,Bala, Balasubramanian Devi,Perumal, Subbu,Menendez, J. Carlos
experimental part, p. 3248 - 3254 (2011/12/15)
The l-proline-catalyzed synthesis of 7-(aryl)-8-methyl-10-phenyl-5H- benzo[h]pyrazolo-[3,4-b]quinoline-5,6(10H)-diones via the four-component sequential reaction of phenylhydrazine, 3-aminocrotononitrile, substituted benzaldehydes and 2-hydroxynaphthalene-1,4-dione is described. This "on water" protocol proceeds in high atom economy and leads to the generation of two rings, together with two C-C, one C-N and two CN bonds in a single operation. The environmental advantages of the method include short reaction time, excellent yield, easy work-up, and the absence of extraction and chromatographic purification steps. The Royal Society of Chemistry.
