1347762-59-7Relevant academic research and scientific papers
Bioinspired imidazo[1,2-a:4,5-c’]dipyridines with dual antiproliferative and anti-migrative properties in human cancer cells: The SAR investigation
Alzain, Abdulrahim A.,Brisson, Lucie,Delaye, Pierre-Olivier,Pénichon, Mélanie,Chadet, Stéphanie,Besson, Pierre,Chevalier, Stéphan,Allouchi, Hassan,Mohamed, Magdi A.,Roger, Sébastien,Enguehard-Gueiffier, Cécile
, (2021/04/09)
Herein, we report the design, synthesis and evaluation of novel bioinspired imidazo[1,2-a:4,5c’]dipyridines. The structural optimization identified four anti-proliferative compounds. Compounds 11, 18, 19 and 20 exhibited excellent anticancer activities in
Grignard reagent-promoted 6-endo-dig cyclization: Instantaneous synthesis of original dipyrido[1,2-a:3′,4′-d]imidazole
Oudot, Romain,Costes, Philippe,Allouchi, Hassan,Pouvreau, Mélanie,Abarbri, Mohamed,Gueiffier, Alain,Enguehard-Gueiffier, Cécile
, p. 9576 - 9581 (2011/12/14)
Dipyrido[1,2-a:3′,4′-d]imidazole derivatives can be readily synthetized from various 3-alkyne-2-cyanoimidazo[1,2-a]pyridines via an efficient Grignard reagent-promoted 6-endo-dig cyclization of nitrile to alkynes. A previous optimization of the Sonogashir
