13480-33-6

Basic information

• Product Name: 1-ISOPROPYL-4-METHYLPIPERAZINE
• Synonyms: 1-ISOPROPYL-4-METHYLPIPERAZINE
• CAS NO: 13480-33-6
• Molecular Formula: C₈H₁₈N₂
• Molecular Weight: 142.24
• Mol File: 13480-33-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-ISOPROPYL-4-METHYLPIPERAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-ISOPROPYL-4-METHYLPIPERAZINE(13480-33-6)
• EPA Substance Registry System: 1-ISOPROPYL-4-METHYLPIPERAZINE(13480-33-6)

Safety Data

• Hazardous Substances Data: 13480-33-6(Hazardous Substances Data)

Upstream product

• 75-31-0 isopropylamine 
• 51-75-2 nitrogen mustard 

Downstream Products

• 140-79-4 N,N'-dinitrosopiperazine 

Relevant articles and documents

Nitrolysis of Tertiary Amines: Piperidines, Piperazines, Bisdimethylaminoalkanes, and Functionalized Methyldialkylamines

Preparative amounts of mono- and di-nitrosamines were obtained from aliphatic cyclic and acyclic tertiary monamines and diamines by treatment with dinitrogen tetraoxide in carbon tetrachloride at 0 - 45 deg C.N-Methyl- and N-ethyl-piperidines (1) and (2) gave N-nitrosopiperidine (15), but N-isopropyl- and N-t-butyl-piperidines (3) and (4) did not.N-Methyl-, N-ethyl-, N-isopropyl- and N-t-butyl-N'-methylpiperazines (5) - (8) gave N,N'-dinitrosopiperazine (22) (in 90 percent, 81 percent, 55 percent, and 8 percent yields, respectively) and the diamine (8) also gave N-t-butyl-N'-dinitrosopiperazine (23) (45 percent).The N'-nitroso and the N'-nitro derivatives of N-methylpiperazine were similarly converted into N,N'-dinitroso- and N-nitroso-N'-nitropiperazines (22) (45 percent) and (30) (53 percent).Bisdimethylaminoalkanes (Me2N)2(CH2)n (10) - (14) gave bismethylnitrosaminoalkanes 2(CH2)n (24) - (27) and dimethylnitrosamine (28): n=1 (0 percent, 90 percent); n=2 (68 percent, 0 percent); n=3 (48 percent, 43 percent); n=4 (41 percent, 38 percent); n=6 (58 percent, 35 percent). β-Dimethylaminopropionitrile (18), 1-methylnitrosamino-2-dimethylaminoethane (17), and α-dimethylaminoacetic acid (19) gave the corresponding nitrosoamines by replacement of an N-methyl group.