140-79-4 Usage
Description
N,N'-DINITROSOPIPERAZINE, also known as DNP, is a pale yellow solid with chemical properties that make it a significant compound in certain scientific and industrial applications. It is known for its ability to induce nasopharyngeal carcinoma (NPC) and exhibits organ specificity to the nasopharyngeal epithelium.
Uses
Used in Pharmaceutical Industry:
N,N'-DINITROSOPIPERAZINE is used as a research compound for studying the development and progression of nasopharyngeal carcinoma (NPC). Its organ specificity to the nasopharyngeal epithelium makes it a valuable tool in understanding the mechanisms behind this type of cancer and potentially developing targeted therapies.
Used in Toxicology Research:
As a compound that induces nasopharyngeal carcinoma, N,N'-DINITROSOPIPERAZINE can be used in toxicology research to study the effects of various substances on the nasopharyngeal epithelium and to develop methods for mitigating the harmful effects of such substances.
Used in Chemical Synthesis:
Due to its unique chemical properties, N,N'-DINITROSOPIPERAZINE may also be used as an intermediate or reagent in the synthesis of other compounds, particularly in the fields of pharmaceuticals, agrochemicals, and materials science. Its pale yellow solid form makes it suitable for various chemical reactions and processes.
Safety Profile
Suspected carcinogen
with experimental carcinogenic,
neoplastigenic, tumorigenic, and teratogenic
data. Poison by ingestion, subcutaneous, and
intraperitoned routes. Experimental
reproductive effects. Human mutation data
reported. When heated to decomposition it
emits toxic fumes of NOx. See also NNITROSO COMPOUNDS.
Check Digit Verification of cas no
The CAS Registry Mumber 140-79-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,4 and 0 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 140-79:
(5*1)+(4*4)+(3*0)+(2*7)+(1*9)=44
44 % 10 = 4
So 140-79-4 is a valid CAS Registry Number.
140-79-4Relevant articles and documents
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Ray,Rakshit
, p. 1 (1913)
-
Facile N-nitrosation of secondary amines using poly(N,N'-dibromo-Nethylene- benzene-1,3-disulfonamide) and N,N,N′,N′-tetrabromobenzene-1,3- disulfonamide/NaNO2 under mild conditions
Ghorbani-Vaghei, Ramin,Shiri, Lotfi,Ghorbani-Choghamarani, Arash
, p. 204 - 208 (2013)
In this research project, a combination of poly(N,N′-dibromo-N- ethylene-benzene-1,3-disulfonamide) [PBBS] and/or (N,N,N′,N′- tetrabromobenzene-1,3-disulfonamide) [TBBDA] with sodium nitrite in the presence of wet SiO2 (50% w/w) was used as an efficient nitrosating agent for the conversion of secondary amines to their corresponding nitroso compounds. N-Nitrosation reaction has been performed in dichloromethane at room temperature under mild and heterogeneous conditions. The reaction is operationally simple and corresponding products were achieved in good to excellent yields.
Deuterated diphenylaminopyrimidine compound
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Paragraph 0109; 0110; 0111; 0112; 0113; 0114, (2017/05/10)
The invention belongs to the field of medicine, and relates to a deuterated diphenylaminopyrimidine compound or a pharmaceutically acceptable salt thereof, and more particularly to a compound of the formula (I) or a pharmaceutically acceptable salt thereof, a preparation process thereof, a pharmaceutical composition thereof and application thereof in the treatment of a cell proliferative disease.
N-nitrosation of secondary amines using supported perchloric acid on silica gel and stereoselectivity study of nitrosated products
Goudarziafshar, Hamid,Ghorbani-Choghamarani, Arash,Hadian, Laila
, p. 1272 - 1276 (2014/04/03)
N-Nitrosation of different types of secondary amines has been proceeded using supported perchloric acid on silica gel and sodiume nitrite under heterogeneous conditions. The operational system is simple and high pure products can be easily isolated with good to high yields.
