13480-43-8

Usage

Uses

Used in Pharmaceutical Industry:
5,8-dichloropyrazino[2,3-d]pyridazine is used as a key intermediate in the development of new drugs and medications. Its unique structure allows for the creation of novel compounds with potential therapeutic effects.
Used in Materials Science:
5,8-dichloropyrazino[2,3-d]pyridazine is used as a component in the development of novel materials with specific electronic or optical properties. Its chemical properties and structure may contribute to the creation of materials with enhanced performance in various applications.

InChI:InChI=1/C6H2Cl2N4/c7-5-3-4(6(8)12-11-5)10-2-1-9-3/h1-2H

Upstream product

• 4744-50-7 2,3-pyrazinedicarboxylic anhydride 
• 13480-40-5 pyrazino<2,3-d>pyridazine-5,8-dione 

Relevant academic research and scientific papers

Structural identification between phthalazine-1,4-diones and n-aminophthalimides via vilsmeier reaction: Nitrogen cyclization and tautomerization study

N-aminophthalimides and phthalazine 1,4-diones were synthesized from isobenzofuran1,3-dione, isoindoline-1,3-dione, furo [3,4-b] pyrazine-5,7-dione, or 1H-pyrrolo [3,4-c] pyridine-1,3dione with monohydrate hydrazine to carry out the 5-exo or 6-endo nitrogen cyclization under the different reaction conditions. Based on the control experimental results, 6-endo thermodynamic hydrohydrazination and kinetical 5-exo cyclization reactions were individually selective formation. Subsequently, Vilsmeier amidination derivatization was successfully developed to probe the structural divergence between N-aminophthalimide 2 and phthalazine 1,4-dione 3. On the other hand, the best tautomerization of N-aminophthalimide to diazinone was also determined under acetic acid mediated solution.