13480-40-5

Usage

Uses

Used in Pharmaceutical Research:
6,7-Dihydropyrazino[2,3-d]pyridazine-5,8-dione is used as a potential drug scaffold for the development of new pharmaceuticals due to its unique structural features and potential biological activity. Its complex ring system and dione functional group offer opportunities for the design of novel therapeutic agents.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 6,7-Dihydropyrazino[2,3-d]pyridazine-5,8-dione serves as a promising starting point for the synthesis of new compounds with potential therapeutic applications. Its structural complexity allows for various modifications and functionalizations, enabling the exploration of its pharmacological properties and the optimization of its biological activity.
Note: Since the provided materials do not specify particular applications or industries for 6,7-Dihydropyrazino[2,3-d]pyridazine-5,8-dione, the uses listed above are general and based on the compound's potential in pharmaceutical research and medicinal chemistry. Further research and development may reveal specific applications in various industries.

InChI:InChI=1/C6H4N4O2/c11-5-3-4(6(12)10-9-5)8-2-1-7-3/h1-2H,(H,9,11)(H,10,12)

Upstream product

• 4744-50-7 2,3-pyrazinedicarboxylic anhydride 
• 6164-77-8 pyrazine-2,3-dicarboxylic acid dimethyl ester 
• 89663-10-5 pyrazine-2,3-dicarboxylic anhydride 1,4-dioxide 
• 67-56-1 methanol 

Downstream Products

• 13480-43-8 5,8-Dichlorpyrazino<2,3-d>pyridazin 
• 89663-11-6 pyrazino<2,3-d>pyridazine-2,3,5,8-tetraone 

Relevant academic research and scientific papers

Structural identification between phthalazine-1,4-diones and n-aminophthalimides via vilsmeier reaction: Nitrogen cyclization and tautomerization study

N-aminophthalimides and phthalazine 1,4-diones were synthesized from isobenzofuran1,3-dione, isoindoline-1,3-dione, furo [3,4-b] pyrazine-5,7-dione, or 1H-pyrrolo [3,4-c] pyridine-1,3dione with monohydrate hydrazine to carry out the 5-exo or 6-endo nitrogen cyclization under the different reaction conditions. Based on the control experimental results, 6-endo thermodynamic hydrohydrazination and kinetical 5-exo cyclization reactions were individually selective formation. Subsequently, Vilsmeier amidination derivatization was successfully developed to probe the structural divergence between N-aminophthalimide 2 and phthalazine 1,4-dione 3. On the other hand, the best tautomerization of N-aminophthalimide to diazinone was also determined under acetic acid mediated solution.

PYRIDAZINES CONDENSED WITH A HETERO RING, III

The cleavage of the pyrazine ring by means of hydrazine hydrate was studied on various model compounds having the pyrazinopyridazine skeleton.The method developed makes possible the preparation of 4,5-diaminopyridazinediones (4a-c) from pyrazino2,

Heterocyclic Analogues of Phthalhydrazides: Cyclic Hydrazides of Pyridine 1-Oxide and Pyrazine 1,4-Dioxide Dicarboxylic Acids

The synthesis of N-oxides of the cyclic hydrazides of pyridine and pyrazine o-dicarboxylic acids is described.Pyridopyridazine-5,8-dione 1-oxide, pyridopyridazine-1,4-dione 6-oxide, and pyrazinopyridazine-5,8-dione 1,2-dioxide, were obtained by direct oxidation of the parent hydrazides with peracetic acid.The pyridopyridazine derivatives were also unambiguously synthesized by treating the anhydrides or diesters of the relevant carboxylic acid 1-oxides with hydrazine hydrate.