134888-96-3Relevant academic research and scientific papers
AMINOPYRROLIDINE COMPOUND
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Page/Page column 61, (2009/01/24)
Disclosed is an aminopyrrolidine compound represented by the formula [I] or a pharmaceutically acceptable salt thereof. The compound or the salt is useful as a prophylactic/therapeutic agent for mode disorder such as depression, anxiety disorder, anorexia, cachexia, pain and drug dependence, whose action relies on the MC4 receptor antagonistic effect.
Synthesis and immunosuppressant activity of pyrazole carboxamides
Wang, Alan X.,Xie, Qinghua,Lane, Ben,Mollison, Karl W.,Hsieh, Gin C.,Marsh, Kennan,Sheets, Michael P.,Luly, Jay R.,Coghlan, Michael J.
, p. 2787 - 2792 (2007/10/03)
A series of novel pyrazole carboxamides sis disclosed that demonstrate strong immunosuppressant activity in rodent and human mixed leukocyte response (MLR) assays (IC50 1 μM). The synthesis, biological activity, mode of action, and pharmacokinetic properties of this new lead series are discussed.
