134890-52-1

Upstream product

• 18300-87-3 ethyl 2-cyano-3-p-tolylacrylate 
• 2017-88-1 ethyl (E)-2-cyano-3-p-tolylacrylate 
• 104-87-0 4-methyl-benzaldehyde 
• 105-56-6 ethyl 2-cyanoacetate 
• 35768-29-7 ethyl 3-(4-chlorophenyl)-2-cyanooxirane-2-carboxylate 

Downstream Products

• 134890-55-4 3-(1-Methyl-1H-imidazol-2-ylsulfanyl)-2-oxo-3-p-tolyl-propionic acid ethyl ester 
• 104-87-0 4-methyl-benzaldehyde 
• 1187-46-8 ethyl bromocyanoacetate 
• 191152-68-8 3-Chloro-2-cyano-2-hydroxy-3-p-tolyl-propionic acid ethyl ester 

Relevant academic research and scientific papers

Hypervalent Iodine(III)-Catalyzed Epoxidation of β-Cyanostyrenes

A convenient approach for the synthesis of β-cyanoepoxides is illustrated by iodine(III)-catalyzed epoxidation of electron-deficient β-cyanostyrenes, wherein the active catalytic iodine(III) species was generated in situ. The epoxidation of β-cyanostyrenes was performed using 10 molpercent PhI as precatalyst in the presence of 2.0 equivalents Oxone as an oxidant and 2.4 equivalents of TFA as an additive at room temperature under ultrasonic radiations. The β-cyanoepoxides were isolated in good to excellent yields in a short reaction time.

Epoxidation of vinyl cyanides by calcium hypochlorite under catalyst- and solvent-free conditions

In this paper, epoxidation of a wide range of alkenes by calcium hypochlorite (Ca(OCl)2) was investigated under catalyst- and solvent-free conditions. It was noticed that the highest yield was achieved with crushing, when the reaction was betwe

Reaction of Li2NiBr4/THF with oxiranes: unexpected behavior of glycidic esters

The complex Li2NiBr4/THF usually gives bromohydrins from epoxides but reacts with α-ester epoxides or α-keto epoxides to generate a carbene species which was trapped with maleimide. - Keywords: epoxides / carbenes / dilithium tetrabromonickelate