134891-13-7Relevant academic research and scientific papers
Decarboxylative Nazarov Cyclization-Based Chirality Transfer for Asymmetric Synthesis of 2-Cyclopentenones
Komatsuki, Keiichi,Kozuma, Akane,Saito, Kodai,Yamada, Tohru
supporting information, p. 6628 - 6632 (2019/09/03)
Asymmetric synthesis of 2-cyclopentenones was achieved by chirality transfer based on Lewis acid catalyzed decarboxylative Nazarov cyclization of optically active cyclic enol carbonates, which are prepared by silver-catalyzed carbon dioxide incorporation into optically pure propargyl alcohols. The stereochemistry at the 4,5-positions of the 2-cyclopentenones was cleanly constructed by reflecting the stereochemistry of the starting materials. This method could be applied to various substrates to obtain the corresponding products in high yields with highly efficient chirality transfer.
Palladium-catalysed arylation of allylic alcohols: Highly selective synthesis of β-aromatic carbonyl compounds or β-aromatic α,β-unsaturated alcohols
Jeffery
, p. 2121 - 2124 (2007/10/02)
The outcome of the coupling of aromatic halides with allylic alcohols can be highly controlled and the reaction directed at will towards the forrmation of either β-aromatic carbonyl or β-aromatic αβ-unsaturated alcohol compounds.
