134896-17-6

Basic information

• Product Name: 1,6-di-O-benzyl-3,4-O-methylethylidene-L-iditol
• Synonyms: 1,6-di-O-benzyl-3,4-O-methylethylidene-L-iditol
• CAS NO: 134896-17-6
• Molecular Weight: 402.488
• Mol File: 134896-17-6.mol

Chemical Properties

• CAS DataBase Reference: 1,6-di-O-benzyl-3,4-O-methylethylidene-L-iditol(CAS DataBase Reference)
• NIST Chemistry Reference: 1,6-di-O-benzyl-3,4-O-methylethylidene-L-iditol(134896-17-6)
• EPA Substance Registry System: 1,6-di-O-benzyl-3,4-O-methylethylidene-L-iditol(134896-17-6)

Safety Data

• Hazardous Substances Data: 134896-17-6(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 94925-98-1 3,4-O-methylethylidene-D-mannitol 
• 63699-97-8 1,2:5,6-dianhydro-3,4-O-methylethylidene-L-iditol 
• 100-51-6 benzyl alcohol 

Downstream Products

• 914982-52-8 1,6-di-O-benzyl-2,5-di-O-methanesulfonyl-3,4-O-methylethylidene-L-iditol 
• 156487-67-1 3,6-di-O-t-butyldiphenylsilyl-4,5-O-isopropylidene-D-myo-inositol 
• 156487-66-0 (S)-2-(tert-Butyl-diphenyl-silanyloxy)-2-{(4S,5S)-5-[(S)-1-(tert-butyl-diphenyl-silanyloxy)-2-hydroxy-ethyl]-2,2-dimethyl-[1,3]dioxolan-4-yl}-ethanol 
• 226931-88-0 {(R)-2-Benzyloxy-1-[(4R,5R)-5-((R)-2-benzyloxy-1-tert-butoxycarbonylamino-ethyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-ethyl}-carbamic acid tert-butyl ester 
• 206655-92-7 2,5-diazido-1,6-di-O-benzyl-2,5-dideoxy-3,4-O-methylethylidene-D-mannitol 
• 206655-94-9 (4R,5R,6R,7R)-4,7-dibenzyloxymethyl-5,6-dihydroxy-5,6-O-methylethylidene-2-(N-benzyl)-imino-1,3-diazepane 
• 206655-93-8 (4R,5R,6R,7R)-4,7-dibenzyloxymethyl-5,6-dihydroxy-5,6-O-methylethylidene-1,3-diazepan-2-thione 
• 267895-52-3 2,5-diamino-1,6-di-O-benzyl-2,5-dideoxy-3,4-O-methylethylidene-D-mannitol 
• 156487-65-9 (4S,5S)-4,5-Bis-[(S)-2-benzyloxy-1-(tert-butyl-diphenyl-silanyloxy)-ethyl]-2,2-dimethyl-[1,3]dioxolane 

Relevant articles and documents

Synthesis of C2-symmetric guanidino-sugars as potent inhibitors of glycosidases

A series of enantiomerically pure C2-Symmetric guanidino-sugars was synthesized from D-mannitol. The first method described involves direct opening of a bis-epoxide by guanidine, whereas the second one deals with a mercury-catalyzed transformation of a cyclic thiourea into a N,N',N'- trisubstituted guanidine as a key step. The biological activity of these compounds towards several glycosidases has been evaluated. One of them (5) was found to selectively inhibit α-L-fucosidase of bovin kidney (2.8 μM). (C) 2000 Elsevier Science Ltd.

Synthesis of C2-symmetric bis(cyclic isothioureas) as potent inhibitors of glycosidases

Enantiopure C2-symmetric bis(cyclic isothioureas), considered as potent inhibitors of glycosidases, have been synthesized from D-mannitol. The key step involved a mercuriccatalyzed transformation of a cyclic 1,3- thiazolidine-2-thione into a 2-

Synthesis of C2-symmetrical cyclic guanidino-sugars from D-mannitol

An efficient method for the synthesis of C2-symmetrical cyclic guanidino-sugars has been developed from 1,2:5,6-dianhydro-3,4-O-methylethylidene-D-mannitol or L-iditol.

A Stereoselective Route to Enantiomerically Pure myo-Inositol Derivatives Starting from D-Mannitol

A carbocyclization route to inositols starting from alditols has been developed involving as a key step a stereoselective intramolecular pinacol coupling of a 1,6-dialdehyde promoted by samarium diiodide.This route has been applied to the synthesis of ena