1349199-41-2Relevant academic research and scientific papers
Macrocyclic Aryl-Nickel(II) Complexes: Synthesis, Structure, and Reactivity Studies
Yang, Chi,Wu, Wen-Di,Zhao, Liang,Wang, Mei-Xiang
, p. 5167 - 5174 (2015)
The synthesis, characterization, and reactivity of the monoaryl-Ni(II) compound 2 and the diaryl-Ni(II) compound 4 formed through the direct electrophilic metalation of two macrocyclic azacalix[m]arene[n]pyridine ligands are described. Compound 4 was much more stable in protic solvents and acids than the monoaryl-Ni(II) compound 2. Moreover, 2 can react with a variety of nucleophiles, resulting in the formation of C-C, C-O, C-Br, and C-N bonds. In contrast, compound 4 exhibited very inert reactivity upon reaction with a large numberof nucleophiles. Interestingly, compound 2 was also capable of reacting with several less bulky alkyl halides to form new C-C bonds, while the same procedure is inapplicable to 4. The study reported in this work provides a thorough investigation on the reactivity of aryl-Ni(II) species that should facilitate comprehension of the detailed mechanism of nickel-catalyzed C-H functionalization.
Regiospecific functionalization of azacalixaromatics through copper-mediated aryl C-H activation and C-O bond formation
Wang, Zu-Li,Zhao, Liang,Wang, Mei-Xiang
supporting information; experimental part, p. 6560 - 6563 (2012/02/04)
Regiospecific functionalization of tetraazacalix[1]arene[3]pyridines at the lower rim position of the benzene ring was achieved conveniently from their cross-coupling reaction with both aliphatic alcohols including chiral primary and secondary alcohols an
