134961-18-5 Usage
Heterocyclic compound
quinazoline and azepane rings The compound consists of two heterocyclic rings, which are rings containing both carbon and nitrogen atoms, contributing to its complex structure and potential biological activity.
Potential applications
Medicinal chemistry 2-(azepan-1-yl)-4-chloroquinazoline has potential uses in the field of medicinal chemistry, particularly in the development of pharmaceutical drugs.
4-chloro substituent
Specific properties and activities The presence of the 4-chloro group on the quinazoline ring can provide specific properties and activities to the compound, making it potentially useful in treating certain diseases or conditions.
Therapeutic uses
Further research and studies Additional research and studies on 2-(azepan-1-yl)-4-chloroquinazoline may reveal its potential therapeutic uses and benefits in the field of medicine, contributing to the development of new drugs and treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 134961-18-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,4,9,6 and 1 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 134961-18:
(8*1)+(7*3)+(6*4)+(5*9)+(4*6)+(3*1)+(2*1)+(1*8)=135
135 % 10 = 5
So 134961-18-5 is a valid CAS Registry Number.
134961-18-5Relevant articles and documents
Reaction of N-Substituted Cyclic Amines with 2,4-Dichloroquinazoline, 2,4-Dichloropyrimidine, and its 5-Methyl Derivative
Yoshida, Kenji,Taguchi, Masahiro
, p. 919 - 922 (2007/10/02)
The reaction of N-substituted cyclic amines with 2,4-dichloroquinazoline 2 and 2,4-dichloro-5-methyl-pyrimidine 3b afforded 2-amino-4-chloroquinazolines and 2-amino-4-chloro-5-methylpyrimidines, respectively.However, the reaction of these amines with 2,4-dichloropyrimidine 3a afforded not only 2-amino-4-chloropyrimidines but also the isomeric 4-amino-2-chloropyrimidines.The regioselectivity of these reactions was considered to be determined by the steric nature of substrates 2, 3a and 3b.
