134987-79-4Relevant academic research and scientific papers
Regiochemistry in aryl radical cyclisations (5-exo versus 6-endo) of N-vinylic 2-iodobenzamides
Ishibashi, Hiroyuki,Ohata, Kohei,Niihara, Michiyo,Sato, Tatsunori,Ikeda, Masazumi
, p. 547 - 554 (2007/10/03)
Bu3SnH-mediated aryl radical cyclisations of a range of N-vinylic 2-iodobenzamides 10 were examined. The enamides 10a-d gave exclusively the 5-exo cyclisation products 11a-d, whereas the enamides 10e,f having a phenyl substituent on the vinylic carbon ato
Free radical cyclizations leading to four-membered rings. I. Betalactam production using tributyltin hydride
Fremont, Susan L.,Belletire, John L.,Ho, Douglas M.
, p. 2335 - 2338 (2007/10/02)
Use of HSnBu3 for the reductive cyclization of suitable enamides having a bromide substituent alpha to the carbonyl group affords beta-lactams in good yields.
