1349980-80-8

Downstream Products

• 1349980-81-9 (3aR,4R,6aS)-octahydrocyclopenta[c]pyrrol-4-ol 
• 1351143-19-5 (3aR,4R,6aS)-4-phenyl-2-[6-(trifluoromethyl)pyridin-2-yl]octahydrocyclopenta[c]pyrrol-4-ol 
• 1351143-38-8 (3aR,4S,6aS)-4-(3-fluorophenoxy)-2-[6-(trifluoromethyl)pyridin-2-yl]octahydrocyclopenta[c]pyrrole 
• 1349980-83-1 (3aR,4R,6aS)-2-[6-(trifluoromethyl)pyridin-2-yl]octahydrocyclopenta[c]pyrrol-4-yl 4-bromobenzenesulfonate 
• 1349979-96-9 C₂₁H₃₀F₃N₃O₂ 
• 1349979-71-0 C₂₁H₃₀F₃N₃O 
• 1349979-69-6 C₂₁H₃₀F₃N₃O 
• 1228026-07-0 tert-butyl (S)-1-((3aR,4S,6aS)-2-benzyloctahydrocyclopenta[c]pyrrol-4-ylamino)-4-methyl-1-oxopentan-2-yl(methyl)carbamate 
• 1228028-62-3 N₂-ethyl-4-methyl-N₁-((3aR,4S,6aS)-2-{[4-(trifluoromethyl)phenyl]sulfonyl}octahydrocyclopenta[c]pyrrol-4-yl)-L-leucinamide 
• 1228028-65-6 N₂-isopropyl-4-methyl-N₁-((3aR,4S,6aS)-2-{[4-(trifluoromethyl)phenyl]sulfonyl}octahydrocyclopenta[c]pyrrol-4-yl)-L-leucinamide 
• 1449789-75-6 C₂₄H₂₈F₃N₃O₃S 
• 1228028-00-9 N₂,4-dimethyl-N₁-((3aR,4S,6aS)-2-{[4-(trifluoromethyl)phenyl]sulfonyl}octahydrocyclopenta[c]pyrrol-4-yl)-L-leucinamide 
• 1228027-93-7 3-methyl-N₁-((3aR,4S,6aS)-2-{[4-(trifluoromethyl)phenyl]sulfonyl}octahydrocyclopenta[c]pyrrol-4-yl)-L-valinamide 
• 1228028-04-3 4-methyl-N₁-((3aR,4S,6aS)-2-{[4-(trifluoromethyl)phenyl]sulfonyl}octahydrocyclopenta[c]pyrrol-4-yl)-L-leucinamide 

Relevant academic research and scientific papers

Synthesis and SAR of 4-aminocyclopentapyrrolidines as orally active N-type calcium channel inhibitors for inflammatory and neuropathic pain

A novel series of N-type calcium channel inhibitors have been discovered. Optimization of potency and HT-ADME properties provides 4- aminocyclopentapyrrolidines with analgesic efficacy after oral dosing.

SUBSTITUTED OCTAHYDROCYCLOPENTA[c]PYRROLES AS CALCIUM CHANNEL MODULATORS

The present application relates to calcium channel inhibitors containing compounds of formula (I) wherein a, R1, R2, R3, and R4 are as defined in the specification. The present application also relates to compos