135-45-5

Basic information

• Product Name: N-(2,5-DIMETHOXYPHENYL) BENZAMIDE
• Synonyms: N-(2,5-DIMETHOXYPHENYL) BENZAMIDE;2',5'-dimethoxybenzanilide
• CAS NO: 135-45-5
• Molecular Formula: C₁₅H₁₅NO₃
• Molecular Weight: 257.28
• EINECS: 205-192-1
• Mol File: 135-45-5.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 328.9°Cat760mmHg
• Flash Point: 152.7°C
• Appearance: /
• Density: 1.189g/cm³
• Storage Temp.: 2-8°C
• CAS DataBase Reference: N-(2,5-DIMETHOXYPHENYL) BENZAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2,5-DIMETHOXYPHENYL) BENZAMIDE(135-45-5)
• EPA Substance Registry System: N-(2,5-DIMETHOXYPHENYL) BENZAMIDE(135-45-5)

Safety Data

• Hazardous Substances Data: 135-45-5(Hazardous Substances Data)

Usage

General Description

N-(2,5-DIMETHOXYPHENYL) BENZAMIDE is a chemical compound that belongs to the class of benzamides. It is a white to off-white solid substance, typically used in research and manufacturing processes. N-(2,5-DIMETHOXYPHENYL) BENZAMIDE has potential applications in the field of pharmaceuticals, agrochemicals, and material sciences. Its chemical structure includes a benzene ring attached to an amide functional group and a dimethoxyphenyl substituent. N-(2,5-DIMETHOXYPHENYL) BENZAMIDE may have various properties and uses, depending on its specific applications and methods of synthesis.

Upstream product

• 98-88-4 benzoyl chloride 
• 102-56-7 2,5-dimethoxyaniline 
• 2100-42-7 2-chloro-1,4-dimethoxybenzene 
• 55-21-0 benzamide 
• 591-50-4 iodobenzene 
• 3467-59-2 2,5-dimethoxyacetanilide 
• 199620-14-9 chromium⁽⁰⁾ hexacarbonyl 
• 221541-73-7 N-(2,5-dimethoxyphenyl)thiobenzamide 

Downstream Products

• 92-20-6 N-(2,5-Dimethoxy-4-nitrophenyl)benzamide 
• 60890-09-7 2-benzamido-1,4-benzoquinone 
• 116496-29-8 5-hydroxy-2-phenylbenzoxazole 
• 1616268-53-1 4-([1,4'-bipiperidin]-1'-ylmethyl)-2-phenylbenzo[d]oxazol-5-ol 
• 221541-78-2 N-(6-Bromo-4,7-dimethoxy-2-phenyl)benzothiazole 
• 221541-74-8 N-(4-bromo-2,5-dimethoxyphenyl)thiobenzamide 
• 221541-83-9 6-Bromo-4,7-dioxo-2-phenylbenzothiazole 
• 221541-76-0 4,7-dimethoxy-2-phenyl-1,3-benzothiazole 
• 221541-80-6 4,7-Dioxo-2-phenylbenzothiazole 
• 262436-51-1 N-[2,5-dimethoxy-4-(p-tolylsulfonylamino)phenyl]thiobenzamide 

Relevant articles and documents

Unique ring expansion of a 6-3 bicyclic ring system forming a functionalized 7-membered ring accelerated by nitrogen functional groups

The treatment of (2-hydroxy-5-oxobicyclo [4.1.0] hept-3-en-3-yl) carbamic acid esters and (2-hydroxy-5-oxobicyclo [4.1.0] hept-3-en-3-yl) benzamide with TMSCl gave 7-membered ring compounds in good yields. The structure of the substituent at the C3 position of the cyclohexene ring is crucial for this ring expansion. The reaction mechanism is thought to involve the formation of a norcaradiene (bicyclo [4.1.0] hept-2,4-diene) structure and subsequent electrocyclic reaction.

Natural Abenquines and Their Synthetic Analogues Exert Algicidal Activity against Bloom-Forming Cyanobacteria

Abenquines are natural quinones, produced by some Streptomycetes, showing the ability to inhibit cyanobacterial growth in the 1 to 100 μM range. To further elucidate their biological significance, the synthesis of several analogues (4f-h, 5a-h) allowed us to identify some steric and electronic requirements for bioactivity. Replacing the acetyl by a benzoyl group in the quinone core and also changing the amino acid moiety with ethylpyrimidinyl or ethylpyrrolidinyl groups resulted in analogues 25-fold more potent than the natural abenquines. The two most effective analogues inhibited the proliferation of five cyanobacterial strains tested, with IC50 values ranging from 0.3 to 3 μM. These compounds may be useful leads for the development of an effective strategy for the control of cyanobacterial blooms.

Complexes

A palladium(II) complex of formula (1) or a palladium(II) complex of formula (3). Also, processes for the preparation of the complexes, and their use in carbon-carbon and carbon-heteroatom coupling reactions.