135-94-4

Basic information

• Product Name: 5-Pyrimidinemethanol, 2-methyl-4-(methylamino)-
• Synonyms: 5-Pyrimidinemethanol, 2-methyl-4-(methylamino)-
• CAS NO: 135-94-4
• Molecular Formula: C7H11N3O
• Molecular Weight: 153.18
• Mol File: 135-94-4.mol
• Article Data: 4

Chemical Properties

• Melting Point: 171.5 °C
• Boiling Point: 321.4±32.0 °C(Predicted)
• Appearance: /
• Density: 1 +-.0.06 g/cm3(Predicted)
• PKA: 13.40±0.10(Predicted)
• CAS DataBase Reference: 5-Pyrimidinemethanol, 2-methyl-4-(methylamino)-(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Pyrimidinemethanol, 2-methyl-4-(methylamino)-(135-94-4)
• EPA Substance Registry System: 5-Pyrimidinemethanol, 2-methyl-4-(methylamino)-(135-94-4)

Safety Data

• Hazardous Substances Data: 135-94-4(Hazardous Substances Data)

Upstream product

• 53135-24-3 ethyl 3,4-dihydro-4-oxo-2-methylpyrimidine-5-carboxylate 
• 102495-25-0 ethyl 2-methyl-4-(methylamino)pyrimidine-5-carboxylate 
• 698-30-6 5-hydroxymethyl-2-methyl-3H-pyrimidin-4-one 
• 731766-78-2 4-chloro-5-chloromethyl-2-methyl-pyrimidine 

Relevant articles and documents

CYCLIC AMINOMETHYL PYRIMIDINE DERIVATIVE

The present invention provides a cyclic aminomethyl pyrimidine derivative and a pharmaceutically acceptable salt thereof with high selectivity for dopamine D4 receptors, which are useful for treating a disease such as attention deficit hyperactivity disorder. Specifically, a compound of formula (1) or a pharmaceutically acceptable salt thereof is provided, wherein n and m are independently 1 or 2; Ra is C1-6 alkyl group, C3-6 cycloalkyl group, or amino group; Rb is hydrogen atom, C1-6 alkyl group or the like, provided that when Ra is amino group, then Rb is hydrogen atom; Rc1 and Rc2 are independently hydrogen atom, or C1-6 alkyl group; Rd1 and Rd2 are independently hydrogen atom, fluorine atom or the like; ring Q is an optionally-substituted pyridyl group or an optionally-substituted isoquinolyl group; and the bond having a dashed line is a single or double bond.

Research on the function of the amino group in thiaminepyrophosphate (Cocarboxylase). 3. Synthesis and biochemical features of a 4' varied analogue of thiaminepyrophosphate

-