698-30-6

Usage

Uses

Used in Pharmaceutical Industry:
5-(Hydroxymethyl)-2-methylpyrimidin-4-ol is used as a precursor in the synthesis of nucleoside analogs for their potential applications in pharmaceuticals and antiviral drugs. Its unique structure allows for the development of compounds that can target specific viral processes, offering new avenues for treatment.
Used in Chemical Industry:
As an important intermediate, 5-(Hydroxymethyl)-2-methylpyrimidin-4-ol is utilized in the synthesis of other organic compounds. Its presence in various chemical reactions contributes to the creation of a wide range of products, underlining its versatility and importance in chemical synthesis processes.
Used in Antiviral Drug Development:
5-(Hydroxymethyl)-2-methylpyrimidin-4-ol is employed as a key component in the development of antiviral drugs. Its role in the synthesis of nucleoside analogs makes it instrumental in creating medications that can inhibit viral replication and reduce the severity of viral infections.
Used in Research and Development:
5-(HYDROXYMETHYL)-2-METHYLPYRIMIDIN-4-OL is used as a subject of research to explore its biological activity and potential therapeutic properties. Ongoing studies aim to understand its interactions with biological systems and its efficacy in treating various conditions, which could lead to new therapeutic applications.

Upstream product

• 53135-24-3 ethyl 4-hydroxy-2-methylpyrimidine-5-carboxylate 
• 5353-05-9 (2-methyl-6-oxo-1,6-dihydro-pyrimidin-5-yl)-acetic acid amide 
• 1749-72-0 5-aminomethyl-2-methyl-3H-pyrimidin-4-one 
• 412035-72-4 (2-methyl-6-oxo-1,6-dihydro-pyrimidin-5-ylmethyl)-carbamic acid ethyl ester 
• 412035-23-5 (2-methyl-6-oxo-1,6-dihydro-pyrimidin-5-yl)-acetic acid hydrazide 
• 14273-42-8 (2-methyl-6-oxo-1,6-dihydro-pyrimidin-5-yl)-acetic acid ethyl ester 

Downstream Products

• 731766-78-2 4-chloro-5-chloromethyl-2-methyl-pyrimidine 
• 135-94-4 4-Methylamino-2-methyl-5-hydroxymethyl-pyrimidin 
• 92-35-3 thiochrome 
• 614-05-1 oxythiamine chloride hydrochloride 
• 117026-52-5 5-(2-hydroxy-ethyl)-4-methyl-3-(2-methyl-6-oxo-1,6-dihydro-pyrimidin-5-ylmethyl)-thiazolium; bis-(4-phenylazo-benzenesulfonate ) 
• 123965-06-0 5-(2-hydroxy-ethyl)-4-methyl-3-(2-methyl-6-oxo-1,6-dihydro-pyrimidin-5-ylmethyl)-thiazolium; [4-(4-dimethylamino-phenylazo)-benzenesulfonate ] 

Relevant academic research and scientific papers

Thiamine Biosynthesis in Yeast - Evaluation of 4-Hydroxy-5-hydroxymethyl-2-methylpyrimidine as a Precursor

The putative role of 4-hydroxy-5-hydroxymethyl-2-methylpyrimidine 2 as a late precursor in the biosynthesis of thiamine 1 by Saccharomyces cerevisiae has been examined using the deuteriated derivative 2a.To enable measurement of deuterium incorporation into the pyrimidine ring fragment of 1, a procedure for the degradation of 1 to the aniline derivative 6 using thiaminase I from Bacillus thiaminolyticus has been developed.While 4-amino-2-methyl-5-hydroxymethylpyrimidine 3a was incorporated into thiamine, deuterium from hydroxy-pyrimidine 2a was not incorporated to any significant extent, indicating that amination of compound 2 is not a late step in the biosynthesis of the pyrimidine ring.