135-95-5

Usage

Uses

Used in Pharmaceutical Synthesis:
(5-amino-2-methoxy-phenyl)methanol is used as a building block for the synthesis of various pharmaceuticals and organic compounds. Its unique structure, which includes an amino group and a methoxy group attached to a benzene ring, allows it to be a versatile component in the creation of diverse medicinal agents.
Used in Drug Development:
In the field of drug development, (5-amino-2-methoxy-phenyl)methanol is utilized as a key intermediate in the formulation of new drugs. Its presence in the molecular structure can influence the pharmacological properties of the final product, potentially enhancing efficacy and selectivity for specific therapeutic targets.
Used in Organic Chemistry Research:
(5-amino-2-methoxy-phenyl)methanol is also used as a reagent in organic chemistry research. Its ability to participate in various chemical reactions, such as substitution, addition, and condensation, makes it a valuable tool for exploring new synthetic pathways and developing novel organic compounds.
Used in Industrial Product Development:
Beyond pharmaceuticals, (5-amino-2-methoxy-phenyl)methanol may have applications in the development of other industrial products. Its chemical properties could be harnessed to create new materials with specific characteristics, such as improved stability, reactivity, or biocompatibility, depending on the industry's needs.

InChI:InChI=1/C8H11NO2/c1-11-8-3-2-7(9)4-6(8)5-10/h2-4,10H,5,9H2,1H3

Upstream product

• 5804-49-9 2-methoxy-5-nitrophenylmethanol 
• 22802-67-1 methyl 2-methoxy-5-aminobenzoate 
• 34841-11-7 methyl 2-methoxy-5-nitrobenzoate 
• 25016-02-8 2-methoxy-5-nitrobenzaldehyde 

Downstream Products

• 1013068-79-5 C₁₂H₁₅NO₃ 
• 943513-53-9 C₃₃H₃₄FN₃O₅ 
• 1111235-36-9 C₂₀H₁₇IN₄O₄S 
• 1187660-10-1 C₁₇H₁₅ClN₄O₂ 
• 1187660-37-2 C₃₈H₅₇N₇O₆ 
• 1187660-91-8 C₃₆H₅₂N₈O₅ 
• 1187660-59-8 C₃₄H₄₆N₆O₅ 
• 1187660-18-9 C₃₄H₄₇N₇O₅ 
• 1187660-19-0 C₃₂H₄₃N₇O₅ 
• 1187660-58-7 C₂₆H₃₃N₅O₆S 
• 1187660-82-7 C₂₇H₃₅ClN₆O₃ 
• 1187660-36-1 C₂₇H₃₆N₆O₄ 
• 1187660-17-8 C₂₆H₃₄N₆O₄ 
• 1187660-12-3 C₂₅H₃₁N₅O₄ 

Relevant academic research and scientific papers

Bicyclic compositions and methods for modulating a kinase cascade

The invention relates to compounds and methods for modulating one or more components of a kinase cascade.

Further studies on hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitors toward improved replicon cell activities: Benzimidazole and structurally related compounds bearing the 2-morpholinophenyl moiety

Following the discovery of JTK-109 (1) as a potent inhibitor of hepatitis C virus NS5B RNA-dependent RNA polymerase, [(a) Hirashima, S.; Suzuki, T.; Ishida, T.; Noji, S.; Yata, S.; Ando, I.; Komatsu, M.; Ikeda, S.; Hashimoto, H. J. Med. Chem. 2006, 49, 4721. (b) Hashimoto, H.; Mizutani, K.; Yoshida, A. Int. Patent Appl. WO 01/47883, 2001.] further studies toward the improvement of the cellular potency have been performed. A greater than 40-fold improvement was achieved through replacing the biphenyl moiety with a 2-morpholinophenyl group and the benzimidazole ring with the tetracyclic scaffold to afford compound 7 with an excellent replicon potency (EC50 = 7.6 nM).

QUINAZOLINE DERIVATIVES

The invention concerns quinazoline derivatives of Formula (I) or a pharmaceutically-acceptable salt, solvate or pro-drug thereof, wherein each of X1, p, R1, q, R2, R3, R4, R5, Ring A, r and R6 has any of the meanings defined hereinbefore in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use in the treatment of cell proliferative disorders or in the treatment of disease states associated with angiogenesis and/or vascular permeability.

QUINAZOLINE DERIVATIVES FOR USE AGAINST CANCER

The invention concerns quinazoline derivatives of Formula (I) or a pharmaceutically-acceptable salt, solvate or pro-drug thereof, wherein each of p, R1, q, R2, R3, R4, R5, Ring A, X1, R6, r and R7 has any of the meanings defined in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use in the treatment of cell proliferative disorders or in the treatment of disease states associated with angiogenesis and/or vascular permeability.

Protein kinase and phosphatase inhibitors and methods for designing them

The present invention provides a method for identifying inhibitors of protein kinases and/or protein phosphatases. Methods are also provided for inhibiting protein kinase and/or protein phosphatase activity. Specific non-peptide protein tyrosine kinase and/or protein phosphatase inhibitors are provided. The protein kinase or protein phosphatase inhibitors of the present invention may be used to treat a number of conditions in patients, including cancer, psoriasis, arthrosclerosis, immune system activity, Type II diabetes, and obesity.

N-phenyl-N-acetamidoglycinamides, their preparation and medicaments containing them

Compounds of formula: STR1 in which R1 represents a hydrogen atom or an alkyl, alkoxycarbonyl or an unsubstituted or substituted phenyl radical, R2 represents a hydrogen atom or an unsubstituted or substituted alkyl radical, R3 represents an alkyl, phenylalkyl, indanyl, cycloalkylalkyl or an unsubstituted or substituted phenyl radical, or R2 and R3 form a heterocycle together with the nitrogen atom to which they are attached, and R4 represents an unsubstituted or substituted phenyl radical, a naphthyl, indolyl or quinolyl radical or a phenylamino radical in which the phenyl ring is unsubstituted or substituted, their preparation and medicaments containing them.