25016-02-8

Basic information

• Product Name: 2-METHOXY-5-NITROBENZALDEHYDE
• Synonyms: AKOS B028867;2-METHOXY-5-NITROBENZALDEHYDE;2-methoxy-5-nitro-benzaldehyd;Benzaldehyde, 2-methoxy-5-nitro-;5-Nitro-o-anisaldehyde;5-Nitro-o-anisaldehyde
• CAS NO: 25016-02-8
• Molecular Formula: C₈H₇NO₄
• Molecular Weight: 181.15
• Product Categories: Aldehydes;C8;Carbonyl Compounds
• Mol File: 25016-02-8.mol
• Article Data: 17

Chemical Properties

• Melting Point: 89-92 °C(lit.)
• Boiling Point: 336.7 °C at 760 mmHg
• Flash Point: 172.3 °C
• Appearance: WHITE TO YELLOW POWDER OR CRYSTALS
• Density: 1.322 g/cm³
• Vapor Pressure: 0.00011mmHg at 25°C
• Refractive Index: 1.59
• Storage Temp.: Inert atmosphere,Room Temperature
• Solubility: very soluble in Dimethylformamide
• CAS DataBase Reference: 2-METHOXY-5-NITROBENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHOXY-5-NITROBENZALDEHYDE(25016-02-8)
• EPA Substance Registry System: 2-METHOXY-5-NITROBENZALDEHYDE(25016-02-8)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 25016-02-8(Hazardous Substances Data)

Usage

General Description

2-Methoxy-5-nitrobenzaldehyde is a chemical compound with the molecular formula C8H7NO4. It is an organic compound that contains a benzene ring with a methoxy group and a nitro group attached to it, as well as an aldehyde functional group. It is used as a precursor in the synthesis of various pharmaceuticals and agrochemicals. It is also used in the production of dyes, pigments, and other organic compounds. This chemical is known for its yellowish color and is typically handled and stored with care due to its potential for hazardous effects on human health and the environment.

InChI:InChI=1/C8H7NO4/c1-13-8-3-2-7(9(11)12)4-6(8)5-10/h2-5H,1H3

Upstream product

• 67-56-1 methanol 
• 27996-87-8 2-fluoro-5-nitrobenzaldehye 
• 60-29-7 diethyl ether 
• 10496-75-0 2-methoxy-5-nitrobenzylnitrile 
• 5197-28-4 2-bromo-4-nitroanisole 
• 121124-97-8 3-formyl-4-methoxyphenylboronic acid 
• 100-17-4 para-methoxynitrobenzene 
• 4885-02-3 Dichloromethyl methyl ether 
• 124-41-4 sodium methylate 
• 6361-21-3 2-chloro-5-nitrobenzaldehyde 
• 93-06-1 2-chloromethyl-4-nitroanisole 
• 6968-37-2 2-Methoxy-5-nitro-benzaldehyd-dimethylacetal 
• 1011-54-7 2-methoxycinnamic acid 
• 97-51-8 5-Nitrosalicylaldehyde 

Downstream Products

• 1254102-46-9 3-(((tert-butyldimethylsilyl)oxy)methyl)-4-methoxyaniline 
• 64437-80-5 5-Nitro-2-methoxy-benzaldoxim 

Relevant articles and documents

AMINE-SUBSTITUTED HETEROCYCLIC COMPOUNDS AS EHMT2 INHIBITORS, SALTS THEREOF, AND METHODS OF SYNTHESIS THEREOF

The present disclosure relates to amine-substituted heterocyclic compounds. The present disclosure also relates to pharmaceutical compositions containing these compounds and methods of treating a disorder (e.g., cancer) by administering an amine-substituted heterocyclic heterocyclic compound disclosed herein or a pharmaceutical composition thereof to subjects in need thereof. The present disclosure also relates to the use of such compounds for research or other non-therapeutic purposes.

Shining new light on the spiropyran photoswitch: A photocage decides between cis-trans or spiro-merocyanine isomerization

Photochromic molecules from the spiropyran family are known to undergo light-induced interconversion between the colorless spiro- and the colored merocyanine forms. Here, we show for the first time that small structural modifications open up for an additional photoisomerization mode: reversible cis-trans isomerization of the merocyanine. Moreover, the introduction of a photocage allows for light-activated switching between the two modes.

Synthesis of nitroolefins and nitroarenes under mild conditions

1,3-Disulfonic acid imidazolium nitrate {[Dsim]NO3} was prepared and characterized as a new ionic liquid and nitrating agent for the ipso-nitration of various arylboronic acids and nitro-Hunsdiecker reaction of different α,β-unsaturated acids and benzoic acid derivatives, by in situ generation of NO2 to give various nitroarenes and nitroolefins without using any cocatalysts and solvents under mild conditions.