1350150-90-1

Basic information

• Product Name: C₂₄H₁₉Cl₂F₃N₂O₆S
• CAS NO: 1350150-90-1
• Molecular Weight: 591.392
• Mol File: 1350150-90-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₄H₁₉Cl₂F₃N₂O₆S(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₄H₁₉Cl₂F₃N₂O₆S(1350150-90-1)
• EPA Substance Registry System: C₂₄H₁₉Cl₂F₃N₂O₆S(1350150-90-1)

Safety Data

• Hazardous Substances Data: 1350150-90-1(Hazardous Substances Data)

Upstream product

• 175205-54-6 2-chloro-4-(trifluoromethyl)benzenesulfonyl chloride 
• 721948-25-0 C₁₇H₁₇ClN₂O₄ 

Relevant articles and documents

Discovery and optimization of CRTH2 and DP dual antagonists

A series of phenylacetic acid derivatives was discovered as CRTH2 antagonists. Modification of the series led to compounds that are also antagonists of DP. Since activation of CRTH2 and DP are believed to play key roles in mediating responses of asthma and other immune diseases, this series was optimized to increase the dual antagonistic activities and improve pharmacokinetic properties. These efforts led to selection of AMG 009 as a clinical candidate.