135028-04-5Relevant articles and documents
N-Amination Using N-Methoxycarbonyl-3-phenyloxaziridine. Direct Access to Chiral Nβ-Protected α-Hydrazinoacids and Carbazates
Vidal, Joelle,Drouin, Jacques,Collet, Andre
, p. 435 - 437 (2007/10/02)
Primary and secondary amines =NH, including α-aminoacids, can be converted under mild conditions to the corresponding carbazates =N-NH-CO2Me, on reaction with N-methoxycarbonyl-3-phenyloxaziridine 1.
α-ALKYLATION OF ACYCLIC AMINO ACIDS WITH SELF-REPRODUCTION OF THE CENTER OF CHIRALITY. A NEW ROUTE TO (S)-(+)-α-ALKYLATED ASPARTIC ACIDS.
Fadel, Antoine,Salaun, Jacques
, p. 2243 - 2246 (2007/10/02)
The amino acids 1a-d (alanine, phenylalanine, valine and methionine) are alkylated by ethyl bromoacetate, with inversion of configuration, to provide readily with high stereoselectivity the α-alkylated aspartic acids 9a-d through the chiral enolates 7a-d