1350351-04-0

Basic information

• Product Name: 3-ethynyl-5-(4-(isopropylsulfonyl)phenyl)pyrazin-2-amine
• Synonyms: 3-ethynyl-5-(4-(isopropylsulfonyl)phenyl)pyrazin-2-amine
• CAS NO: 1350351-04-0
• Molecular Weight: 301.369
• Mol File: 1350351-04-0.mol

Chemical Properties

• CAS DataBase Reference: 3-ethynyl-5-(4-(isopropylsulfonyl)phenyl)pyrazin-2-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-ethynyl-5-(4-(isopropylsulfonyl)phenyl)pyrazin-2-amine(1350351-04-0)
• EPA Substance Registry System: 3-ethynyl-5-(4-(isopropylsulfonyl)phenyl)pyrazin-2-amine(1350351-04-0)

Safety Data

• Hazardous Substances Data: 1350351-04-0(Hazardous Substances Data)

Upstream product

• 1232423-98-1 tert-butyl N-(3-ethynyl-5-(4-(isopropylsulfonyl)phenyl)pyrazin-2-yl)N-tertbutoxycarbonyl-carbamate ? 
• 1350351-56-2 tert-butyl N-tert-butoxycarbonyl-N-[5-(4-isopropylsulfonylphenyl)-3-(2-trimethylsilylethynyl)pyrazin-2-yl]carbamate 
• 1350351-55-1 5-(4-isopropylsulfonylphenyl)-3-(2-trimethylsilylethynyl)pyrazin-2-amine 
• 1349151-83-2 3-bromo-5-(4-(isopropylsulfonyl)phenyl)pyrazin-2-amine 
• 1349151-81-0 5-(4-(isopropylsulfonyl)phenyl)pyrazin-2-amine 
• 850567-98-5 4-(isopropylsulfonyl)phenylboronic acid 

Downstream Products

• 1416740-14-1 N-(2-(4-(isopropylsulfonyl)phenyl)-5-tosyl-5H-pyrrolo[2,3-b]pyrazin-7-yl)benzamide 
• 1416739-71-3 N-(2-(4-(isopropylsulfonyl)phenyl)-5H-pyrrolo[2,3-b]pyrazin-7-yl)benzamide 
• 1353571-16-0 2-(4-isopropylsulfonylphenyl)-7-(3-pyridyl)-5H-pyrrolo[2,3-b]pyrazine 
• 1353571-90-0 2-(4-isopropylsulfonylphenyl)-5-(p-tolylsulfonyl)-7-(3-pyridyl)pyrrolo[2,3-b]pyrazine 
• 1353571-89-7 7-iodo-2-(4-(isopropylsulfonyl)phenyl)-5-(p-tolylsulfonyl)pyrrolo[2,3-b]pyrazine 
• 1353571-88-6 7-iodo-2-(4-(isopropylsulfonyl)phenyl)-5H-pyrrolo[2,3-b]pyrazine 
• 1353571-87-5 2-(4-(isopropylsulfonyl)phenyl)-5H-pyrrolo[2,3-b]pyrazine 
• 1353571-19-3 1-[3-[5-[2-(4-isopropylsulfonylphenyl)-5H-pyrrolo[2,3-b]pyrazin-7-yl]isoxazol-3-yl]phenyl]ethanamine 
• 1353571-96-6 tert-butyl N-[1-[3-[5-[2-(4-isopropylsulfonylphenyl)-5H-pyrrolo[2,3-b]pyrazin-7-yl]isoxazol-3-yl]phenyl]ethyl]carbamate 
• 1353571-18-2 5-[2-(4-isopropylsulfonylphenyl)-5H-pyrrolo[2,3-b]pyrazin-7-yl]-3-phenyl-isoxazole 
• 1353571-95-5 5-[2-(4-isopropylsulfonylphenyl)-5-(p-tolylsulfonyl)pyrrolo[2,3-b]pyrazin-7-yl]-3-phenyl-isoxazole 
• 1353571-94-4 7-ethynyl-2-(4-isopropylsulfonylphenyl)-5-(p-tolylsulfonyl)pyrrolo[2,3-b]pyrazine 
• 1353571-93-3 7-ethynyl-2-(4-isopropylsulfonylphenyl)-5H-pyrrolo[2,3-b]pyrazine 
• 1353571-92-2 2-[2-(4-isopropylsulfonylphenyl)-5-(p-tolylsulfonyl)pyrrolo[2,3-b]pyrazin-7-yl]ethynyl-trimethyl-silane 

Relevant articles and documents

COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE

The present invention relates to pyrrolopyrazines compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various diseases, disorders, and conditions using the compounds of this invention; processes for preparing the compounds of this invention; intermediates for the preparation of the compounds of this invention; and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena; the study of intracellular signal transduction pathways mediated by such kinases; and the comparative evaluation of new kinase inhibitors. The compounds of this invention have formula I wherein the variables are as defined herein

COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE

The present invention relates to pyrazine and pyridine compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating various dis

PYRROLO- PYRAZINE DERIVATIVES USEFUL AS INHIBITORS OF ATR KINASE

The present invention relates to pyrrolopyrazines compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention; methods of treating of various disea