135036-53-2

Upstream product

• 63421-72-7 4-[(methyl-sulfonyl)amino]benzoyl chloride 
• 135036-52-1 4-(3-chlorophenyl)-1-[(3,4-dimethoxyphenyl)methyl]-2-piperazinemethanamine 

Downstream Products

• 135036-08-7 N-<<4-(3-chlorophenyl)piperazin-2-yl>methyl>-4-<(methylsulfonyl)amino>benzamide 

Relevant academic research and scientific papers

Synthesis, cardiac electrophysiology, and β-blocking activity of novel arylpiperazines with potential as class II/III antiarrhythmic agents

A series of novel arylpiperazines have been prepared in an attempt to incorporate both class II (β-receptor blocking) and class III antiarrhythmic properties in a single molecule. The key step in the preparation of the new compounds involves a regioselect

2-substituted-1(4)-aryl piperazines and the process for their preparation

This invention relates to novel 2-substituted-1(4)-aryl piperazines and to a process for their preparation. The compounds of this invention have been found to have cardiovascular, primarily antiarrhythmic effects and are of the following general formula I