63421-72-7

Basic information

• Product Name: Benzoyl chloride, 4-[(methylsulfonyl)amino]-
• CAS NO: 63421-72-7
• Molecular Formula: C8H8ClNO3S
• Molecular Weight: 233.675
• Mol File: 63421-72-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzoyl chloride, 4-[(methylsulfonyl)amino]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoyl chloride, 4-[(methylsulfonyl)amino]-(63421-72-7)
• EPA Substance Registry System: Benzoyl chloride, 4-[(methylsulfonyl)amino]-(63421-72-7)

Safety Data

• Hazardous Substances Data: 63421-72-7(Hazardous Substances Data)

Upstream product

• 7151-76-0 4-(methylsulfonamido)benzoic acid 
• 7440-44-0 pyrographite 

Downstream Products

• 116855-32-4 N-<2-(diethylamino)ethyl>-4-<(methylsufonyl)amino>-N-phenylbenzamide 
• 123507-50-6 N-<2-(diethylamino)ethyl>-N-(4-ethylphenyl)-4-<(methylsulfonyl)amino>benzamide 
• 116855-41-5 N-<2-(diethylamino)-1-(1-naphthalenyl)ethyl>-4-<(methylsulfonyl)amino>benzamide 
• 116855-42-6 N-<2-(diethylamino)-2-(1-naphthalenyl)ethyl>-4-<(methylsulfonyl)amino>benzamide 
• 123507-54-0 N-<2-(diethylamino)ethyl>-4-<(methylsufonyl)amino>-N-<4-<(methylsulfonyl)amino>phenyl>benzamide 
• 135036-56-5 4-<(methylsulfonyl)amino>-N-<<4-phenyl-1-(phenylmethyl)piperazin-2-yl>methyl>benzamide hydrochloride 
• 135036-24-7 4-[(Methylsulfonyl)amino]-N-[[1-phenyl-4-(phenylmethyl)piperazin-2-yl]methyl] benzamide 
• 135036-53-2 N-[[4-(3-Chlorophenyl)-1-[(3,4-dimethoxyphenyl)methyl]piperazin-2-yl]methyl]-4-[(methylsulfonyl)amino]benzamide 
• 1357294-90-6 N-[4-(6,7-dimethoxy-3-n-butyl-4-oxo-3,4-dihydroquinazolin-2-yl)phenyl]methanesulfonamide 
• 101526-62-9 N-[2-(diethylamino)ethyl]-4-[(methylsulfonyl)amino]benzamide hydrochloride 

Relevant articles and documents

Cytotoxic potential of novel 6,7-dimethoxyquinazolines

Herein, we report the synthesis and cytotoxicity of a series of substituted 6,7-dimethoxyquinazoline derivatives. The cytotoxic activity of all synthesized compounds has been evaluated against HCT116p53+/+ and HCT116p53 -/- colon cancer cells and a HEY ovarian cancer cell line naturally resistant to cisplatin. Nine of the tested compounds showed significant cytotoxicity in all cell lines at 10 μM. The most promising derivative (7c) showed IC50values of 0.7 and 1.7 μM in the two colon cancer cell lines.

Substituted sulfonamidobenzamides, antiarrhythmic agents and compositions thereof

Novel substituted sulfonamidobenzamides are described as useful antiarrhythmic agents. Their use in the treatment of cardiac arrhythmias, especially re-entrant arrhythmias, via the prolongation of the action potential of cardiac tissue is provided. Pharmaceutical formulations containing such compounds are also disclosed.