1350449-72-7Relevant academic research and scientific papers
Inhibition of glutathione S-Transferase M1 by new gabosine analogues is essential for overcoming cisplatin resistance in lung cancer cells
Wang, Chie-Hong,Wu, Ho T.,Cheng, Hau M.,Yen, Tien-Jui,Lu, I-Hsuan,Chang, Hui Chuan,Jao, Shu-Chuan,Shing, Tony K.M.,Li, Wen-Shan
, p. 8574 - 8581 (2012/02/04)
A new class of human GST inhibitors has been identified via rational design approach; we report their discovery, synthesis, inhibitory activity, and synergetic effect in combination with cisplatin against A549 lung cancer cell line. The results of this ef
