1350477-13-2

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 1350477-09-6 (2S,4S)-1-(tert-butoxycarbonyl)-5-oxo-4-phenylaminoproline methyl ester 
• 1032764-56-9 methyl (2S,4S)-5-oxo-4-phenylaminoprolinate 

Relevant academic research and scientific papers

Synthesis of the (2S,4S)-stereoisomers of 4-(indol-1-yl) and 4-arylamino derivatives of 5-oxoproline, proline, and 2-hydroxymethylpyrrolidine

Nucleophilic substitution of the halogen atom in dimethyl (S)-4-bromoglutamate followed by removal of the protecting groups and closure of a lactam ring afforded (2S,4S)-4-(indolin-1-yl)-5-oxoproline. The indoline fragment was oxidized into the indole fra