Cas 1350522-13-2,C17H17BrN2O2

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Check Digit Verification of cas no

The CAS Registry Mumber 1350522-13-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,5,0,5,2 and 2 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1350522-13:
(9*1)+(8*3)+(7*5)+(6*0)+(5*5)+(4*2)+(3*2)+(2*1)+(1*3)=112
112 % 10 = 2
So 1350522-13-2 is a valid CAS Registry Number.

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1350522-13-2Relevant academic research and scientific papers

Synthesis and SAR of a novel metabotropic glutamate receptor 4 (mGlu 4) antagonist: Unexpected 'molecular switch' from a closely related mGlu4 positive allosteric modulator

Utley, Thomas,Haddenham, Dustin,Salovich, James M.,Zamorano, Rocio,Vinson, Paige N.,Lindsley, Craig W.,Hopkins, Corey R.,Niswender, Colleen M.

, p. 6955 - 6959 (2012/01/06)

Herein we report the discovery and SAR of a novel antagonist of metabotropic glutamate receptor 4 (mGlu4). The antagonist was discovered via a molecular switch from a closely related mGlu4 positive allosteric modulator (PAM). This antagonist (VU0448383) displays an IC50 value of 8.2 ± 0.4 μM and inhibits an EC80 glutamate response by 63.1 ± 6.6%.

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1350522-13-2

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