135055-59-3

Upstream product

• 26863-15-0 N-(2',4'-dinitrophenyl)-4-phenylpyridinium chloride 
• 613-94-5 benzoic acid hydrazide 
• 56000-34-1 1-Amino-4-phenyl-pyridinium-mesitylensulfonat 
• 98-88-4 benzoyl chloride 
• 23031-08-5 benzoyl(pyridin-1-ium-1-yl)amide 
• 24388-23-6 2-phenyl-4,4,5,5-tetramethyl-1,3,2-dioxoborole 
• 98-80-6 phenylboronic acid 
• 939-23-1 p-phenylpyridine 

Downstream Products

• 135055-71-9 N-(benzoylamino)-4-phenyl-1,2,3,6-tetrahydropyridine 
• 1429338-03-3 benzoyl(2-neopentyl-4-phenylpyridinium-1-yl)azanide 

Relevant academic research and scientific papers

Benzoyl peroxide promoted radical ortho-alkylation of nitrogen heteroaromatics with simple alkanes and alcohols

A catalytic amount of benzoyl peroxide (BPO)-initiated cross-dehydrogenative coupling reaction of N-iminopyridine ylides with simple alkanes and alcohols leads to the corresponding 2-alkylpyridines with high regioselectivity in moderate to good yields without an additional reduction step to remove the activated group. A catalytic amount of benzoyl peroxide (BPO)-initiated cross-dehydrogenative coupling reaction of N-iminopyridine ylides with simple alkanes and alcohols has been developed. The strategy allowed convenient access to various 2-alkylpyridines in moderate to good yields without an additional reduction step to remove the activated group.

Silver-catalyzed direct C-H arylation of N -iminopyridinium ylides with arylboronic acids

A novel direct C-H arylation of N-iminopyridinium ylides with arylboronic acids has been developed. This reaction is performed at ambient temperature using inexpensive reagents: catalytic silver nitrate in the presence of potassium persulfate co-oxidant and give pyridyl arylation derivatives in moderate to good yields.

Synthesis of N-benzoylamino-1,2,3,6-tetrahydropyridine derivatives as potential anti-inflammatory agents

(Chemical Equation Presented) N-Benzoylamino-1,2,3,6-tetrahydropyridines 9a-q were synthesized from 4-substituted pyridines in four steps. Amination of pyridines was carried out to prepare intermediate N-aminopyridinium mesylates using mesytelenesulfonyl hydroxmate (MSH) as aminating agent. N-aminopyridinium mestylates reacted with appropriately substituted acyl chlorides to form N-ylides as stable crystalline solids. Partial reduction of N-ylides with mild reducing agent afforded N-benzoylamino-1,2,3,6-tetrahydropyridines in fair to good yields.