1350558-50-7Relevant academic research and scientific papers
Stereoselective total synthesis of the putative structure of nitraraine
Arioli, Federica,Pérez, Maria,Subrizi, Fabiana,Llor, Núria,Bosch, Joan,Amat, Mercedes
, p. 7740 - 7745 (2014)
After the structure originally proposed for nitraraine was shown to be incorrect by total synthesis, the alternative structure 5 was recently suggested for the alkaloid on biosynthetic grounds and by comparison with the 1H NMR data of tangutorine. The unambiguous synthesis of 5 is reported from tryptophanol and ketodiester 6, via oxazoloquinolone lactam 7. However, the melting point and 1H NMR data of 5 did not match those reported for the natural product.
A practical synthetic route to enantiopure 6-substituted cis-decahydroquinolines
Amat, Mercedes,Navio, Laura,Llor, Nuria,Molins, Elies,Bosch, Joan
, p. 210 - 213 (2012/03/10)
Starting from 4-substituted cyclohexanones, a practical synthetic route to enantiopure 6-substituted cis-decahydroquinolines has been developed, the key steps being a stereoselective cyclocondensation of an unsaturated δ-keto ester derivative with (R)-phenylglycinol and the stereoselective hydrogenation of the resulting tricyclic oxazoloquinolone lactams.
