5202-42-6

Basic information

• Product Name: ethyl 4-(pyrrolidin-1-yl)cyclohex-3-ene-1-carboxylate
• Synonyms: ethyl 4-(pyrrolidin-1-yl)cyclohex-3-ene-1-carboxylate
• CAS NO: 5202-42-6
• Molecular Weight: 223.315
• Mol File: 5202-42-6.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: ethyl 4-(pyrrolidin-1-yl)cyclohex-3-ene-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 4-(pyrrolidin-1-yl)cyclohex-3-ene-1-carboxylate(5202-42-6)
• EPA Substance Registry System: ethyl 4-(pyrrolidin-1-yl)cyclohex-3-ene-1-carboxylate(5202-42-6)

Safety Data

• Hazardous Substances Data: 5202-42-6(Hazardous Substances Data)

Upstream product

• 123-75-1 pyrrolidine 
• 17159-79-4 ethyl 4-oxocyclohexane-1-carboxylate 

Downstream Products

• 5202-43-7 1-(2-Carboxy-aethyl)-cyclohexanon-⁽²⁾-carbonsaeure-⁽⁵⁾-diaethylester 
• 1350558-50-7 methyl 3-(ethoxycarbonyl)-6-oxocyclohexenepropionate 
• 1350558-58-5 C₂₀H₂₃NO₄ 
• 1350558-54-1 C₂₀H₂₃NO₄ 
• 1350558-62-1 C₂₀H₂₅NO₄ 
• 53600-12-7 5-Carbethoxy-2-methyl-indol 
• 5202-39-1 3-(5-carboxy-2-oxo-cyclohexyl)-propionic acid 

Relevant articles and documents

Synthesis of Substituted Anilines from Cyclohexanones Using Pd/C-Ethylene System and Its Application to Indole Synthesis

The synthesis of anilines and indoles from cyclohexanones using a Pd/C-ethylene system is reported. A simple combination of NH4OAc and K2CO3 under nonaerobic conditions was found to be the most suitable to perform this reaction. Hydrogen transfer between cyclohexanone and ethylene generates the desired products. The reaction tolerates a variety of substitutions on the starting cyclohexanones.

A concise one-pot synthesis of trifluoromethyl-containing 2,6-disubstituted 5,6,7,8-tetrahydroquinolines and 5,6,7,8-tetrahydronaphthyridines

5,6,7,8-Tetrahydroquinolines and 5,6,7,8-tetrahydronaphthyridines with appended trifluoromethyl groups are valuable chemotypes in medicinal chemistry due to the presence of a partially-saturated bicyclic ring and metabolically-stable CF3 group. 1H NMR studies were used to optimize the preparation of such compounds, using a three-step/one-pot procedure, to provide novel 2,6-disubstitued derivatives with a tertiary-substituent. Racemic 2,6-disubstituted tetrahydroquinolines were separated by chiral HPLC to provide single enantiomers.

AMIDE DERIVATIVES AS ION-CHANNEL LIGANDS AND PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME

Compounds are disclosed that have a formula represented by the following: (I). The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including