135064-20-9

Usage

InChI:InChI=1/C16H23NO/c1-3-8-17-9-7-14-13(11-17)10-12-5-4-6-15(18-2)16(12)14/h4-6,13-14H,3,7-11H2,1-2H3/t13-,14+/m0/s1

Upstream product

• 138967-86-9 7-Methoxy-2,3-dihydro-1H-indene-2carboxaldehyde-1-acetic acid, ethyl ester 
• 131818-60-5 2-(diethoxymethyl)-4-bromo-7-methoxyindan-1-one 
• 5411-61-0 4-bromo-7-methoxy-2,3-dihydro-1H-inden-1-one 
• 66192-02-7 3-(2-bromo-5-methoxyphenyl)propanoic acid 
• 10516-71-9 3-(3-Methoxy-phenyl)-propionic acid 

Relevant academic research and scientific papers

Synthesis and structure activity relationships of cis- and trans- 2,3,4,4a,9,9a-hexahydro-1H-indeno[2,1-c]pyridines for 5-HT receptor subtypes

A series of cis- and trans-fused hexahydroindeno[2,1-c]pyridines have been prepared and evaluated for affinity and selectivity at the 5-HT(1A) subtype of the serotonin receptor. Using molecular modeling studies we predicted that the 5-methoxy-trans-fused

5-HT selective agents

Substituted 8-alkoxy-1,2,3,3a,8,8a-hexahydroindeno-[1,2-c]pyrroles; 5-alkoxy-2,3,4,4a,9,9a-hexahydro-1H-indeno[2,1-c]pyridines; and 9-alkoxy-2,3,3a,4,5,9a-hexahydro-1H-benz[e]isoindoles are selective 5-HT receptor agents and are thus useful in the treatment of anxiety, depression, and hypertension.