1350712-81-0

Basic information

• Product Name: 2-[1-(3-chloro-phenyl)-1H-imidazol-4-yl]-5-(2-trimethylsilanyl-ethoxymethyl)-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid ((S)-1,2,2-trimethyl-propyl)-amide
• Synonyms: 2-[1-(3-chloro-phenyl)-1H-imidazol-4-yl]-5-(2-trimethylsilanyl-ethoxymethyl)-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid ((S)-1,2,2-trimethyl-propyl)-amide
• CAS NO: 1350712-81-0
• Molecular Weight: 553.179
• Mol File: 1350712-81-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-[1-(3-chloro-phenyl)-1H-imidazol-4-yl]-5-(2-trimethylsilanyl-ethoxymethyl)-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid ((S)-1,2,2-trimethyl-propyl)-amide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[1-(3-chloro-phenyl)-1H-imidazol-4-yl]-5-(2-trimethylsilanyl-ethoxymethyl)-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid ((S)-1,2,2-trimethyl-propyl)-amide(1350712-81-0)
• EPA Substance Registry System: 2-[1-(3-chloro-phenyl)-1H-imidazol-4-yl]-5-(2-trimethylsilanyl-ethoxymethyl)-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid ((S)-1,2,2-trimethyl-propyl)-amide(1350712-81-0)

Safety Data

• Hazardous Substances Data: 1350712-81-0(Hazardous Substances Data)

Upstream product

• 63503-60-6 3-chlorophenylboronic acid 
• 875781-43-4 2-bromo-5H-pyrrolo[2,3-b]pyrazine 
• 1334674-87-1 (2-bromo-5-hydroxymethyl-5H-pyrrolo[2,3-b]pyrazin-7-yl)-methanol 
• 1334674-88-2 (2-bromo-5H-pyrrolo[2,3-b]pyrazin-7-yl)-methanol 
• 1185428-32-3 2-bromo-5H-pyrrolo[2,3-b]pyrazine-7-carbaldehyde 
• 1185428-34-5 2-bromo-5-(2-trimethylsilanyl-ethoxymethyl)-5H-pyrrolo-[2,3-b]pyrazine-7-carbaldehyde 
• 1334674-90-6 2-bromo-5-((2-(trimethylsilyl)ethoxy)methyl)-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid 
• 1350712-80-9 1-(3-chlorophenyl)-4-tributylstannanyl-1H-imidazole 
• 1350712-73-0 2-bromo-5-(2-trimethylsilanyl-ethoxymethyl)-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid ((S)-1,2,2-trimethyl-propyl)-amide 
• 1350712-79-6 4-iodo-1-(3-chlorophenyl)-1H-imidazole 

Downstream Products

• 1350708-34-7 2-[1-(3-chlorophenyl)-1H-imidazol-4-yl]-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid ((S)-1,2,2-trimethyl-propyl)-amide 

Relevant articles and documents

PYRROLO [2, 3 - B] PYRAZINE - 7 - CARBOXAMIDE DERIVATIVES AND THEIR USE AS JAK AND SYK INHIBITORS

The present invention relates to the use of novel pyrrolopyrazine derivatives of Formula (I), wherein the variables Q and R, R2, and R3 are defined as described herein, which inhibit JAK and SYK and are useful for the treatment of auto-immune and inflammatory diseases.